. "Matia\u0161ovic, J\u00E1n" . "Oreskovi\u010D, Zrinka" . "Barto\u0161kov\u00E1, A." . "3" . . "\u0160t\u011Bp\u00E1nov\u00E1, Hana" . "Lev\u00E1, Lenka" . . . . . "P(ED0006/01/01), Z(MZE0002716202)" . . "1090-0233" . "V\u00EDcenov\u00E1, Monika" . . "Gamma delta T lymphocytes are recruited into the inflamed uterus of bitches suffering from pyometra"@en . "Vit\u00E1sek, R." . "Faldyna, Martin" . . "Gamma delta T lymphocytes are recruited into the inflamed uterus of bitches suffering from pyometra"@en . . . . "Canine; Lymphocyte subsets; Flow cytometry; Chemokines; gamma delta Lymphocytes"@en . . . "Oreskovi\u010D, Zrinka" . "Gamma delta T lymphocytes are recruited into the inflamed uterus of bitches suffering from pyometra" . . "194" . . "Gamma delta T lymphocytes are recruited into the inflamed uterus of bitches suffering from pyometra" . "Tur\u00E1nek-Kn\u00F6tigov\u00E1, Pavl\u00EDna" . "000313224300012" . . "8"^^ . "Moore, P. F." . "137703" . . "Ondr\u00E1\u010Dkov\u00E1, Petra" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "11"^^ . . "6"^^ . . . . "Very little is known about the occurrence of immune system cells in the canine uterus. The aim of this study was to generate information about lymphocyte subsets that are present in the healthy canine uterus and that are recruited under inflammatory conditions caused by pyometra. Using immunohistochemistry and flow cytometry, a significant influx of ?? T lymphocytes was found in pyometra samples mainly due to recruitment of ??(+)/CD8(-) T lymphocytes. The relative expression of genes encoding selected cytokines/chemokines was evaluated in samples from healthy and pyometra-affected uteri. Expression of pro-inflammatory cytokines (including IL-1\u00DF, TNF-?, IL-8, IL-17 and IFN-?) and chemokines (including CXCL10, CCL4 and CCL5) was upregulated in pyometra samples confirming the presence of inflammation. In contrast, the expression of the homeostatic chemokine CCL25 and of the anti-inflammatory cytokine IL-10 was downregulated and unchanged, respectively. Copyright c 2012 Elsevier Ltd. All rights reserved."@en . "10.1016/j.tvjl.2012.05.024" . . . "Very little is known about the occurrence of immune system cells in the canine uterus. The aim of this study was to generate information about lymphocyte subsets that are present in the healthy canine uterus and that are recruited under inflammatory conditions caused by pyometra. Using immunohistochemistry and flow cytometry, a significant influx of ?? T lymphocytes was found in pyometra samples mainly due to recruitment of ??(+)/CD8(-) T lymphocytes. The relative expression of genes encoding selected cytokines/chemokines was evaluated in samples from healthy and pyometra-affected uteri. Expression of pro-inflammatory cytokines (including IL-1\u00DF, TNF-?, IL-8, IL-17 and IFN-?) and chemokines (including CXCL10, CCL4 and CCL5) was upregulated in pyometra samples confirming the presence of inflammation. In contrast, the expression of the homeostatic chemokine CCL25 and of the anti-inflammatory cytokine IL-10 was downregulated and unchanged, respectively. Copyright c 2012 Elsevier Ltd. All rights reserved." . "[869E54FE7CE9]" . "Veterinary Journal" . . "RIV/00027162:_____/12:#0000922!RIV13-MZE-00027162" . . "RIV/00027162:_____/12:#0000922" .