. "12" . . . "Musilov\u00E1, Petra" . "Ingraft chimerism in lung transplantation - a study in a porcine model of obliterative bronchiolitis"@en . "Maasilta, P., K." . . . "Aittom\u00E4ki, K." . . "Ingraft chimerism in lung transplantation - a study in a porcine model of obliterative bronchiolitis"@en . "RIV/00027162:_____/11:#0000762!RIV12-MZE-00027162" . "Salminen, Ulla-Stina" . . "Raivio, P. M." . "2"^^ . "[34698E8DADE0]" . . "Alho, H. S." . "204829" . "Respiratory Research" . "We studied the influence of chimerism on bronchial epithelium and obliterative bronchiolitis (OB) development in pigs. Immunosuppressed and unimmunosuppressed bronchial allografts were serially obtained after transplantation. Histology was assessed and the fluorescence in situ hybridization method for Y chromosomes using pig-specific DNA-label was used to detect recipient derived cells in graft epithelium and bronchial wall, and donor cell migration to recipient organs. Early appearance of recipient-derived cells in the airway epithelium appeared predictive of epithelial destruction and of obliteration of the bronchial lumen All allografts with preserved epithelium showed epithelial chimerism throughout the follow-up. Antirejection medication did not prevent, but delayed the appearance of Y chromosome positive cells in the epithelium, or bronchial wall." . . . "Rube\u0161, Ji\u0159\u00ED" . . "1465-9921" . . . "Z(MZE0002716202)" . . "CELL TRANSPLANTATION; AIRWAY DISEASE; CONDITIONING REGIMEN; TOLERANCE; EPITHELIUM; ALLOGRAFTS; REJECTION; MICRODISSECTION; INDUCTION; INJURY"@en . "We studied the influence of chimerism on bronchial epithelium and obliterative bronchiolitis (OB) development in pigs. Immunosuppressed and unimmunosuppressed bronchial allografts were serially obtained after transplantation. Histology was assessed and the fluorescence in situ hybridization method for Y chromosomes using pig-specific DNA-label was used to detect recipient derived cells in graft epithelium and bronchial wall, and donor cell migration to recipient organs. Early appearance of recipient-derived cells in the airway epithelium appeared predictive of epithelial destruction and of obliteration of the bronchial lumen All allografts with preserved epithelium showed epithelial chimerism throughout the follow-up. Antirejection medication did not prevent, but delayed the appearance of Y chromosome positive cells in the epithelium, or bronchial wall."@en . "8"^^ . . . . . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . . . "RIV/00027162:_____/11:#0000762" . "7"^^ . "000291448500001" . "Ingraft chimerism in lung transplantation - a study in a porcine model of obliterative bronchiolitis" . . "P\u00E4iv\u00E4niemi, Outi, E." . "56" . . "Ingraft chimerism in lung transplantation - a study in a porcine model of obliterative bronchiolitis" . . .