"Hubertov\u00E1, D." . "Basel, Switzerland" . . "[C6E82B19FDA8]" . "394965" . "RIV/00027162:_____/08:#0000599" . "In previous work, we found significant associations of horse chromosome 15 microsatellite markers HMSO1 and HTG06 with two horse infections, Rhodococcus equi and Lawsonia intracellularis, respectively. Interleukin-1 beta subunit and interleukin-1 receptor antagonist encoding genes (IL1B and IL1RN) could be considered as candidate genes. Therefore, we identified single nucleotide polymorphisms (SNPs) within three interleukin-1 beta functionally related genes: IL1B, IL1RN and Casp1 (interleukin-1 beta converting enzyme/caspasel encoding gene). Using appropriate restriction fragment length polymorphism (PCR-RFLP) and/or single strand conformation polymorphism (PCR-SSCP) markers, their associations with the two infections by genotyping foals from the original study were tested. A statistically significant association between an intronic SNP of the Casp1 gene with R. equi infection was found. The IL1RN gene was physically localized by fluorescence in-situ hybridization to 15q13-q14." . "Rube\u0161, Ji\u0159\u00ED" . "Single Nucleotide Polymorphisms of Interleukin-1 beta Related Genes and their Associations with Infection in the Horse" . "RIV/00027162:_____/08:#0000599!RIV10-MZE-00027162" . "978-3-8055-8619-1" . . . . "Single Nucleotide Polymorphisms of Interleukin-1 beta Related Genes and their Associations with Infection in the Horse"@en . . "4"^^ . "Single Nucleotide Polymorphisms of Interleukin-1 beta Related Genes and their Associations with Infection in the Horse"@en . "Developments in Biologicals, vol. 132" . . "5"^^ . "Matia\u0161ovic, J\u00E1n" . . . . "Osi\u010Dkov\u00E1, J." . "Ne\u010Des\u00E1nkov\u00E1, M." . . . "Kub\u00ED\u010Dkov\u00E1, Svatava" . . "9"^^ . . . "P(GA523/06/1402), Z(MZE0002716201)" . "Vysko\u010Dil, M." . . "In previous work, we found significant associations of horse chromosome 15 microsatellite markers HMSO1 and HTG06 with two horse infections, Rhodococcus equi and Lawsonia intracellularis, respectively. Interleukin-1 beta subunit and interleukin-1 receptor antagonist encoding genes (IL1B and IL1RN) could be considered as candidate genes. Therefore, we identified single nucleotide polymorphisms (SNPs) within three interleukin-1 beta functionally related genes: IL1B, IL1RN and Casp1 (interleukin-1 beta converting enzyme/caspasel encoding gene). Using appropriate restriction fragment length polymorphism (PCR-RFLP) and/or single strand conformation polymorphism (PCR-SSCP) markers, their associations with the two infections by genotyping foals from the original study were tested. A statistically significant association between an intronic SNP of the Casp1 gene with R. equi infection was found. The IL1RN gene was physically localized by fluorescence in-situ hybridization to 15q13-q14."@en . . . "Ho\u0159\u00EDn, P." . "Karger" . . "Animal Genomics for Animal Health" . "Single Nucleotide Polymorphisms of Interleukin-1 beta Related Genes and their Associations with Infection in the Horse" . . . "horse; interleukin 1 beta; interleukin 1 receptor antagonist; interleukin 1 beta converting enzyme; polymorphism; infection"@en . . . "440"^^ . . "Musilov\u00E1, Petra" .