"1-2" . "Characterisation of immunosuppression in rabbits after infection with myxoma virus"@en . "RIV/00027162:_____/08:#0000353" . "V t\u00E9to studii byly charakterizov\u00E1ny zm\u011Bny v hematologick\u00E9m profilu, zm\u011Bny v zastoupen\u00ED subpopulac\u00ED lymfocyt\u016F a nespecifick\u00E9 prolifera\u010Dn\u00ED aktivit\u011B lymfocyt\u016F z r\u016Fzn\u00FDch lymfoidn\u00EDch kompartment\u016F kr\u00E1l\u00EDk\u016F 2., 4., 6., 9. a 11. den po experiment\u00E1ln\u00ED infekci virem myxomat\u00F3zy. Hematologick\u00E9 zm\u011Bny zahrnovaly leukop\u00E9nii se signifikantn\u00ED lymfop\u00E9nii, neutrofilii, monocyt\u00F3zou a eosinop\u00E9nia. Pokles T lymfocyt\u016F v\u010Detn\u011B CD4+ a CD8+ a vzestup CD79a+ byl pozorov\u00E1n v dr\u00E9nuj\u00EDc\u00ED poplite\u00E1ln\u00ED m\u00EDzn\u00ED uzlin\u011B 4 dny po inokulaci viru. Srovnateln\u00E9 zm\u011Bny byly detekov\u00E1ny v ostatn\u00EDch lymfoidn\u00EDch kompartmentech od 6. dne. Od 9. dne, ve v\u0161ech lymfocyt\u00E1rn\u00EDch kompartmentech krom\u011B dr\u00E9nuj\u00EDc\u00ED poplite\u00E1ln\u00ED uzliny, se zastoupen\u00ED subpopulac\u00ED lymfocyt\u016F vracelo na p\u016Fvodn\u00ED hodnoty. Naopak, prolifera\u010Dn\u00ED aktivita lymfocyt\u016F byla signifikantn\u011B sn\u00ED\u017Een\u00E1 od 4. dne a z\u016Fstala redukovan\u00E1 a\u017E do konce experimentu. Virus byl detekovateln\u00FD v testovan\u00FDch org\u00E1nech v\u017Edy d\u0159\u00EDve ne\u017E nastaly zm\u011Bny v distribuci lymfocyt\u016F nebo v jejich aktivit\u011B."@cs . "Veterinary Microbiology" . "8"^^ . . "In this study changes in haematological profile, changes in lymphocyte subset distribution and proliferation activity of lymphocytes from different lymphoid compartments on the 2nd, 4th, 6th, 9th and 11th day after experimental infection of rabbits with myxoma virus was characterised. Haematological changes included moderate leucopenia with significant lymphopenia, neutrophilia, monocytosis and eosinopenia. A decrease of T and increase of CD79alpha+ were observed in draining popliteal lymph node 4 days after virus inoculation. From day 6, comparable changes were seen in other lymphoid compartments. From day 9, the mentioned lymphocyte subsets tended to reach their original state in all lymphocyte compartments except draining popliteal lymph node. On the other hand, proliferation activity of lymphocytes was significantly reduced from day 4 until the end of experiment. Presence of virus in respective lymphoid compartments preceded changes in lymphocyte subset distribution or lymphocyte activity." . . "Nevor\u00E1nkov\u00E1, Zora" . . . "8"^^ . "Matia\u0161ovic, J\u00E1n" . "Characterisation of immunosuppression in rabbits after infection with myxoma virus"@en . . . . "14"^^ . . . "Charakterizace imunosuprese u kr\u00E1l\u00EDk\u016F po infekci virem myxomat\u00F3zy"@cs . . "Kova\u0159\u010D\u00EDk, Kamil" . . "Charakterizace imunosuprese u kr\u00E1l\u00EDk\u016F po infekci virem myxomat\u00F3zy"@cs . "[3932D76D029C]" . . "Jeklov\u00E1, Edita" . . . "000255990700012" . "Z(MZE0002716201)" . "Kudl\u00E1\u010Dkov\u00E1, Hana" . "RIV/00027162:_____/08:#0000353!RIV09-MZE-00027162" . "In this study changes in haematological profile, changes in lymphocyte subset distribution and proliferation activity of lymphocytes from different lymphoid compartments on the 2nd, 4th, 6th, 9th and 11th day after experimental infection of rabbits with myxoma virus was characterised. Haematological changes included moderate leucopenia with significant lymphopenia, neutrophilia, monocytosis and eosinopenia. A decrease of T and increase of CD79alpha+ were observed in draining popliteal lymph node 4 days after virus inoculation. From day 6, comparable changes were seen in other lymphoid compartments. From day 9, the mentioned lymphocyte subsets tended to reach their original state in all lymphocyte compartments except draining popliteal lymph node. On the other hand, proliferation activity of lymphocytes was significantly reduced from day 4 until the end of experiment. Presence of virus in respective lymphoid compartments preceded changes in lymphocyte subset distribution or lymphocyte activity."@en . "NL - Nizozemsko" . . . . "Myxomatosis; Lymphocyte subsets; Lagomorphs; Flow cytometry"@en . . . . "0378-1135" . . "359544" . "Characterisation of immunosuppression in rabbits after infection with myxoma virus" . . "P\u0161ikal, Ivan" . . "Characterisation of immunosuppression in rabbits after infection with myxoma virus" . "129" . "Lev\u00E1, Lenka" . "Faldyna, Martin" .