. . "Matia\u0161ovic, J\u00E1n" . "Faldyna, Martin" . . . "59" . "endocrine disruptors; estradiol; estrogen receptor alpha; immunohistochemistry; polycyclic aromatic hydrocarbons; rat uterotrophy bioassay; reproductive system"@en . . . . . "[2B37729847DC]" . . "69;76" . . "Experimental and Toxicologic Pathology" . . "1" . "Kummer, Vladim\u00EDr" . "P(GA525/05/2695), Z(MZE0002716201)" . "Ma\u0161kov\u00E1, Jarmila" . . . "Effect of postnatal exposure to benzo(a)pyrene on the uterus of immature rats"@en . . . "RIV/00027162:_____/07:#0000196!RIV08-MZE-00027162" . "Chromosomes of fourteen captive-born mountain reedbucks (Redunca fulvorufula) have been investigated. Chromosomal complement was 2n=56 (FN=60). The mountain reedbuck karyotype consists of two biarmed pairs resulting from two centric fusions involving chromosomes 2;25 and 6;10, respectively. In some animals, 57 chromosomes were detected. Variation in the diploid number was the result of polymorphism for the 6;10 centric fusion. Both X and Y chromosomes are large and acrocentric. The Y chromosome and the proximal part of the X chromosome appeared to stain entirely heterochromatic. The chromosomes X, 9 and 14 appeared to be of caprine type. Chromosomal aberrations have been detected in two of the 14 animals investigated. The de novo formed Robertsonian translocation 56,XX,rob(6;13) was found in one female heterozygote for the fusion 6;10. The double heterozygote was sharing monobrachial homology for chromosome 6."@en . "Effect of postnatal exposure to benzo(a)pyrene on the uterus of immature rats" . "Chromosomes of fourteen captive-born mountain reedbucks (Redunca fulvorufula) have been investigated. Chromosomal complement was 2n=56 (FN=60). The mountain reedbuck karyotype consists of two biarmed pairs resulting from two centric fusions involving chromosomes 2;25 and 6;10, respectively. In some animals, 57 chromosomes were detected. Variation in the diploid number was the result of polymorphism for the 6;10 centric fusion. Both X and Y chromosomes are large and acrocentric. The Y chromosome and the proximal part of the X chromosome appeared to stain entirely heterochromatic. The chromosomes X, 9 and 14 appeared to be of caprine type. Chromosomal aberrations have been detected in two of the 14 animals investigated. The de novo formed Robertsonian translocation 56,XX,rob(6;13) was found in one female heterozygote for the fusion 6;10. The double heterozygote was sharing monobrachial homology for chromosome 6." . . "RIV/00027162:_____/07:#0000196" . . "Zral\u00FD, Zden\u011Bk" . . "Sledovali jsme vliv postnat\u00E1ln\u00ED expozice benzo(a)pyrenu (BaP) na v\u00FDvoj d\u011Blohy, expresi estrogenov\u00E9ho receptoru alfa (ER alfa) a na odpov\u011B\u010F d\u011Blohy na stimulaci estrogenem za pou\u017Eit\u00ED uterotrofn\u00ED bioeseje u potkan\u016F. Novorozenc\u016Fm byl ka\u017Ed\u00FD den po dobu 14 dn\u00ED s.c. aplikov\u00E1n BaP nebo ethynylestradiol nebo vehikulum (kontroln\u00ED skupina). Potkani byli zabiti ve st\u00E1\u0159\u00ED 23 dn\u016F. Postnat\u00E1ln\u00ED aplikace BaP v d\u00E1vk\u00E1ch 1.0 a 10.0 mg/kg zp\u016Fsobila redukci v\u00E1hy d\u011Blohy a sn\u00ED\u017Een\u00ED exprese ER alfa v lumin\u00E1ln\u00EDm epitelu. Zv\u00FD\u0161en\u00ED v\u00E1hy d\u011Blohy a v\u00FD\u0161ky lumin\u00E1ln\u00EDho epitelu po EE stimulaci ve 20-22 dni st\u00E1\u0159\u00ED bylo vy\u0161\u0161\u00ED u v\u0161ech skupin ve srovn\u00E1n\u00ED se skupinou nestimulovanou. Nicm\u00E9n\u011B, uterotrofn\u00ED odpov\u011B\u010F potkan\u016F postnat\u00E1ln\u011B exponovan\u00FDch EE a BaP byla ni\u017E\u0161\u00ED ne\u017E u kontrol. Studie uk\u00E1zala, \u017Ee postnat\u00E1ln\u00ED expozice BaP vyvol\u00E1v\u00E1 zm\u011Bny v konstituci a maturaci ER alfa v d\u011Bloze, co\u017E n\u00E1sledn\u011B vede k naru\u0161en\u00E9mu v\u00FDvoji a funkci d\u011Blohy u imaturn\u00EDch potkan\u016F."@cs . . . "Effect of postnatal exposure to benzo(a)pyrene on the uterus of immature rats"@en . . "5"^^ . "Effect of postnatal exposure to benzo(a)pyrene on the uterus of immature rats" . . "8"^^ . "DE - Spolkov\u00E1 republika N\u011Bmecko" . . "5"^^ . "419051" . "Vliv postnat\u00E1ln\u00ED expozice benzo(a)pyrenu na d\u011Blohu nematurovan\u00FDch potkan\u016F"@cs . . . "Vliv postnat\u00E1ln\u00ED expozice benzo(a)pyrenu na d\u011Blohu nematurovan\u00FDch potkan\u016F"@cs . "0940-2993" .