"2"^^ . "4"^^ . "394487" . "Serotonin1A receptors in the pathophysiology of schizophrenia: development of novel cognition-enhancing therapeutics" . "Serotonin (5-HT) receptors have been suggested to play key roles in psychosis, cognition, and mood via influence on neurotransmitters, synaptic integrity, and neural plasticity. Specifically, genetic evidence indicates that 5-HT1A, 5-HT2A, and 5-HT2C receptor single-nucleotide polymorphisms (SNPs) are related to psychotic symptoms, cognitive disturbances, and treatment response in schizophrenia. Data from animal research suggest the role of 5-HT in cognition via its influence on dopaminergic, cholinergic, glutamatergic, and GABAergic function. This article provides up-to-date findings on the role of 5-HT receptors in endophenotypic variations in schizophrenia and the development of newer cognition-enhancing medications, based on basic science and clinical evidence."@en . "Serotonin1A receptors in the pathophysiology of schizophrenia: development of novel cognition-enhancing therapeutics"@en . "P(1M0517), P(NR8792), P(NR9324)" . . . . "Serotoninov\u00E9 (5-HT) receptory hraj\u00ED kl\u00ED\u010Dovou roli u psych\u00F3zy, kognitivn\u00EDch funkc\u00EDch a n\u00E1lady p\u0159es ovlivn\u011Bn\u00ED neurotransmiter\u016F, synaptick\u00E9 integrity a plasticity. P\u0159edev\u0161\u00EDm genetick\u00E9 studie ukazuj\u00ED, \u017Ee jedno-nukleotidov\u00FD polymorfismus u 5-HT1A, 5-HT2A a 5-HT2C receptor\u016F souvis\u00ED s psychotick\u00FDmi symptomy, kognitivn\u00EDm po\u0161kozen\u00EDm a odpov\u011Bd\u00ED na l\u00E9\u010Dbu u pacient\u016F se schizofreni\u00ED. Data s anim\u00E1ln\u00EDch studi\u00ED upozor\u0148uj\u00ED na v\u00FDzna\u010Dnou \u00FAlohu 5-HT receptor\u016F v kognitivn\u00EDch \u00FAloh\u00E1ch p\u0159es ovlivn\u011Bn\u00ED dopaminergn\u00ED, cholinergn\u00ED, glutam\u00E1tergn\u00ED a GABAergn\u00ED neurotransmise. Tento \u010Dl\u00E1nek shrnuje v\u00FDsledky a v\u00FDvoj nov\u00FDch prokognitivn\u00EDch l\u00E1tek na z\u00E1klad\u011B z\u00E1kladn\u00EDho i klinick\u00E9ho v\u00FDzkumu."@cs . . "Serotonin-1A receptory v patofyziologii schizofrenie: V\u00FDvoj nov\u00E9 terapie posiluj\u00EDc\u00ED kognitivn\u00ED funkce"@cs . . "RIV/00023752:_____/08:00000840" . "10" . "Serotonin1A receptors in the pathophysiology of schizophrenia: development of novel cognition-enhancing therapeutics" . "5-HT1A; 5-HT receptors; cognition; schizophrenia; serotonin; translational research"@en . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "Serotonin (5-HT) receptors have been suggested to play key roles in psychosis, cognition, and mood via influence on neurotransmitters, synaptic integrity, and neural plasticity. Specifically, genetic evidence indicates that 5-HT1A, 5-HT2A, and 5-HT2C receptor single-nucleotide polymorphisms (SNPs) are related to psychotic symptoms, cognitive disturbances, and treatment response in schizophrenia. Data from animal research suggest the role of 5-HT in cognition via its influence on dopaminergic, cholinergic, glutamatergic, and GABAergic function. This article provides up-to-date findings on the role of 5-HT receptors in endophenotypic variations in schizophrenia and the development of newer cognition-enhancing medications, based on basic science and clinical evidence." . . . "Hor\u00E1\u010Dek, Ji\u0159\u00ED" . . "Serotonin-1A receptory v patofyziologii schizofrenie: V\u00FDvoj nov\u00E9 terapie posiluj\u00EDc\u00ED kognitivn\u00ED funkce"@cs . . . "Serotonin1A receptors in the pathophysiology of schizophrenia: development of novel cognition-enhancing therapeutics"@en . . "Sumiyoshi, T." . "Advances in Therapy" . "RIV/00023752:_____/08:00000840!RIV09-MZ0-00023752" . "0741-238X" . "25" . "20"^^ . . . . . . . "Bert, B." . "[3DEAF5285E36]" . . . . . "Buben\u00EDkov\u00E1-Vale\u0161ov\u00E1, V\u011Bra" .