. . "203-207" . "Nov\u00E1k, Tom\u00E1\u0161" . "Souhrn: V mnoha studi\u00EDch byla zji\u0161t\u011Bna souvislost n\u00EDzk\u00E9 plazmatick\u00E9 hladiny cholesterolu a depresivn\u00ED poruchy. M\u00E9n\u011B informac\u00ED je k dispozici o vlivu plasmatick\u00E9 hladiny cholesterolu na odpov\u011B\u010F p\u0159i farmakologick\u00E9 l\u00E9\u010Db\u011B antidepresivy. C\u00EDlem studie bylo ov\u011B\u0159it, zda hladina cholesterolu p\u0159ed l\u00E9\u010Dbou souvis\u00ED s odpov\u011Bd\u00ED na l\u00E9\u010Dbu inhibitory zp\u011Btn\u00E9ho vychyt\u00E1v\u00E1n\u00ED serotoninu (SRI). Metoda: Do retrospektivn\u00ED anal\u00FDzy bylo za\u0159azeno 85 pacient\u016F (61 \u017Een a 24 mu\u017E\u016F), kte\u0159\u00ED byli l\u00E9\u010Den\u00ED nejm\u00E9n\u011B 4 t\u00FDdny (medi\u00E1n 5 t\u00FDdn\u016F) antidepresivy t\u0159\u00EDdy SRI. Depresivn\u00ED symptomatika byla hodnocena na za\u010D\u00E1tku a konci l\u00E9\u010Dby Beckovou sebehodnot\u00EDc\u00ED \u0161k\u00E1lou deprese - kr\u00E1tk\u00E1 verse (BDI-S). Soubor pacient\u016F byl rozd\u011Blen do dvou skupin(norm\u00E1ln\u00ED hladina cholesterolu vs. zv\u00FD\u0161en\u00E1 hladina cholesterolu - ? 200 mg/dl, tj. ? 5, 17 mmol/l).V\u00FDsledky: Odpov\u011Bdi na l\u00E9\u010Dbu (pokles sk\u00F3ru v BDI-S ?50%) dos\u00E1hlo 41% pacient\u016F. Hladina cholesterolu u respond\u00E9r\u016F a non-respond\u00E9r\u016F se neli\u0161ila (p= 0,21). Pod\u00EDly respond\u00E9r\u016F ve skupin\u011B s norm\u00E1ln\u00EDm cholesterolem (43" . "CZ - \u010Cesk\u00E1 republika" . "5"^^ . . . "413570" . . . "Cholesterol a odpov\u011B\u010F na l\u00E9\u010Dbu inhibitory zp\u011Btn\u00E9ho vychyt\u00E1v\u00E1n\u00ED serotoninu (SRI) u pacient\u016F s depresivn\u00ED poruchou: retrospektivn\u00ED studie"@cs . "depressive disorder; response to treatment; serotonin reuptake inhibitors; cholesterol"@en . "Cholesterol and response to treatment with serotonin reuptake inhibitors (SRI) in patients with depressive disorder: a retrospective study"@en . "Psychiatrie" . "1211-7579" . . "\u0160ediv\u00E1, Jolana" . "RIV/00023752:_____/07:00000793!RIV08-MZ0-00023752" . "5"^^ . . . "RIV/00023752:_____/07:00000793" . "Kope\u010Dek, Miloslav" . "Summary: A number of studies reports an association between low cholesterol plasma level and depressive disorder. There is a lack of studies exploring influence over cholesterol plasma level to antidepressant response. The aim of our study is to examine association between cholesterol plasma level before treatment and response to SRI\u00B4s antidepressants. Methods: Our retrospective analyses comprises 85 patients (61 women, 24 men), which were treated with SRI\u00B4s antidepressants for at least 4 weeks (median 5 weeks). Depressive symptomatology was assessed using Beck Depressive Inventory - short version (BDI -S) before and at the end of treatment. The sample of patients was divided into 2 groups (patients with normal cholesterol plasma level vs. patients with high cholesterol level - ?200 mg/dl, i.e. ? 5.17 mmol/l). Results: Forty- one percent of patients reached a response (decrease in BDI-S score ?50%) to treatment. The cholesterol plasma level before treatment did not differ in responders and nonr"@en . . . "11" . "Z(MZ0PCP2005)" . . . "Cholesterol a odpov\u011B\u010F na l\u00E9\u010Dbu inhibitory zp\u011Btn\u00E9ho vychyt\u00E1v\u00E1n\u00ED serotoninu (SRI) u pacient\u016F s depresivn\u00ED poruchou: retrospektivn\u00ED studie" . "[8C2A4E312B6D]" . . "Cholesterol and response to treatment with serotonin reuptake inhibitors (SRI) in patients with depressive disorder: a retrospective study"@en . . . "Cholesterol a odpov\u011B\u010F na l\u00E9\u010Dbu inhibitory zp\u011Btn\u00E9ho vychyt\u00E1v\u00E1n\u00ED serotoninu (SRI) u pacient\u016F s depresivn\u00ED poruchou: retrospektivn\u00ED studie"@cs . "Cholesterol a odpov\u011B\u010F na l\u00E9\u010Dbu inhibitory zp\u011Btn\u00E9ho vychyt\u00E1v\u00E1n\u00ED serotoninu (SRI) u pacient\u016F s depresivn\u00ED poruchou: retrospektivn\u00ED studie" . "Bare\u0161, Martin" . . . . . "4" . "Souhrn: V mnoha studi\u00EDch byla zji\u0161t\u011Bna souvislost n\u00EDzk\u00E9 plazmatick\u00E9 hladiny cholesterolu a depresivn\u00ED poruchy. M\u00E9n\u011B informac\u00ED je k dispozici o vlivu plasmatick\u00E9 hladiny cholesterolu na odpov\u011B\u010F p\u0159i farmakologick\u00E9 l\u00E9\u010Db\u011B antidepresivy. C\u00EDlem studie bylo ov\u011B\u0159it, zda hladina cholesterolu p\u0159ed l\u00E9\u010Dbou souvis\u00ED s odpov\u011Bd\u00ED na l\u00E9\u010Dbu inhibitory zp\u011Btn\u00E9ho vychyt\u00E1v\u00E1n\u00ED serotoninu (SRI). Metoda: Do retrospektivn\u00ED anal\u00FDzy bylo za\u0159azeno 85 pacient\u016F (61 \u017Een a 24 mu\u017E\u016F), kte\u0159\u00ED byli l\u00E9\u010Den\u00ED nejm\u00E9n\u011B 4 t\u00FDdny (medi\u00E1n 5 t\u00FDdn\u016F) antidepresivy t\u0159\u00EDdy SRI. Depresivn\u00ED symptomatika byla hodnocena na za\u010D\u00E1tku a konci l\u00E9\u010Dby Beckovou sebehodnot\u00EDc\u00ED \u0161k\u00E1lou deprese - kr\u00E1tk\u00E1 verse (BDI-S). Soubor pacient\u016F byl rozd\u011Blen do dvou skupin(norm\u00E1ln\u00ED hladina cholesterolu vs. zv\u00FD\u0161en\u00E1 hladina cholesterolu - ? 200 mg/dl, tj. ? 5, 17 mmol/l).V\u00FDsledky: Odpov\u011Bdi na l\u00E9\u010Dbu (pokles sk\u00F3ru v BDI-S ?50%) dos\u00E1hlo 41% pacient\u016F. Hladina cholesterolu u respond\u00E9r\u016F a non-respond\u00E9r\u016F se neli\u0161ila (p= 0,21). Pod\u00EDly respond\u00E9r\u016F ve skupin\u011B s norm\u00E1ln\u00EDm cholesterolem (43"@cs . "Raszka, Michal" . "5"^^ .