. "[882F9DE87B42]" . "77225" . "Hepcidin bound to alpha(2)-macroglobulin reduces ferroportin-1 expression and enhances its activity at reducing serum iron levels"@en . . "Hepcidin is the hormone of iron metabolism that is bound by alpha2-macroglobulin (alpha2M) and its activated counterpart (alpha2M-MA). Serum iron is reduced to a greater extent in mice treated with alpha2Mhepcidin or alpha2M-MAhepcidin relative to unbound hepcidin. Alpha2M retards hepcidin excretion by the kidney, increasing its efficacy. These results are important for understanding hepcidin transport and detection in blood."@en . . "0021-9258" . . . "7"^^ . "RIV/00023736:_____/13:00010741" . . "Huang, M.L.H." . "288" . "Vyoral, Daniel" . "Hepcidin bound to alpha(2)-macroglobulin reduces ferroportin-1 expression and enhances its activity at reducing serum iron levels" . . "10.1074/jbc.M113.471573" . "16"^^ . . . "Hepcidin bound to alpha(2)-macroglobulin reduces ferroportin-1 expression and enhances its activity at reducing serum iron levels"@en . "35" . "1"^^ . "000330619000041" . "Hepcidin bound to alpha(2)-macroglobulin reduces ferroportin-1 expression and enhances its activity at reducing serum iron levels" . "Po\u0148ka, P." . "Austin, C.J.D." . "Hepcidin is the hormone of iron metabolism that is bound by alpha2-macroglobulin (alpha2M) and its activated counterpart (alpha2M-MA). Serum iron is reduced to a greater extent in mice treated with alpha2Mhepcidin or alpha2M-MAhepcidin relative to unbound hepcidin. Alpha2M retards hepcidin excretion by the kidney, increasing its efficacy. These results are important for understanding hepcidin transport and detection in blood." . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "Sari, M.-A." . "hepcidin; iron metabolism; alpha-2-macroglobulin"@en . "Journal of biological chemistry" . "Rahmanto, Y. S." . . . . "RIV/00023736:_____/13:00010741!RIV14-MZ0-00023736" . . "http://dx.doi.org/10.1074/jbc.M113.471573" . "Richardson, D." . . "I" .