"RIV/00023736:_____/13:00009659!RIV14-MZ0-00023736" . "Kodet, R." . "Andr\u00E9, S." . "Galectins are potent effectors of cell adhesion and growth regulation. Their expression as comples network necessitates systematic study of each member of this family. Toward this aim, we here focus on the tandem-repeat-type galectin-9. Its presence is monitored in normal squamous epithelium of the head and neck, the surgical margin, and four types of squamous cell carcinoma. Lectin presence was detected in cells of the basal layer of the epithelium. All galectin-9-negative epithelia showed aberrant positivity for keratins 14 and 19. The surgical margin presented either a normal pattern of galectin-9 and keratin presence or a mosaic-like presence/absence of galectin-9 and aberrant expression of both keratins 14 and 19. All studied specimens of squamous cell carcinoma were negative for galectin-9. When biotinylated galectin-9, or its N-terminal domain, was tested, no significant tissue reactivity for both probes was observed. Neuraminidase treatment generated reactivity to the N-domain." . "8"^^ . "Tachezy, Ruth" . "[D583C128E6AB]" . . "42" . . . . "DK - D\u00E1nsk\u00E9 kr\u00E1lovstv\u00ED" . "Journal of oral pathology & medicine" . "2" . "000314471200008" . . "I, S, V" . "Kaltner, H." . "F\u00EDk, Z." . "Foltynov\u00E1, Eva" . "Loss of adhesion/growth-regulatory galectin-9 from squamous cell epithelium in head and neck carcinomas"@en . . "Chovanec, M." . . "Gabius, H. J." . "0904-2512" . "Kodet, O." . "Valach, J." . "Loss of adhesion/growth-regulatory galectin-9 from squamous cell epithelium in head and neck carcinomas" . . "85442" . . "2"^^ . . . "10.1111/j.1600-0714.2012.01185.x" . . "agglutinin; basal cells; epithelium; keratin; lectin; tumor"@en . "Smetana, K." . "RIV/00023736:_____/13:00009659" . . . . "Maz\u00E1nek, J." . . . . "Loss of adhesion/growth-regulatory galectin-9 from squamous cell epithelium in head and neck carcinomas"@en . "12"^^ . . . . "Loss of adhesion/growth-regulatory galectin-9 from squamous cell epithelium in head and neck carcinomas" . "http://dx.doi.org//10.1111/j.1600-0714.2012.01185.x" . "Galectins are potent effectors of cell adhesion and growth regulation. Their expression as comples network necessitates systematic study of each member of this family. Toward this aim, we here focus on the tandem-repeat-type galectin-9. Its presence is monitored in normal squamous epithelium of the head and neck, the surgical margin, and four types of squamous cell carcinoma. Lectin presence was detected in cells of the basal layer of the epithelium. All galectin-9-negative epithelia showed aberrant positivity for keratins 14 and 19. The surgical margin presented either a normal pattern of galectin-9 and keratin presence or a mosaic-like presence/absence of galectin-9 and aberrant expression of both keratins 14 and 19. All studied specimens of squamous cell carcinoma were negative for galectin-9. When biotinylated galectin-9, or its N-terminal domain, was tested, no significant tissue reactivity for both probes was observed. Neuraminidase treatment generated reactivity to the N-domain."@en .