. "AE - St\u00E1t Spojen\u00E9 arabsk\u00E9 emir\u00E1ty" . "The mammalian target of rapamycin (mTOR) is a downstream mediator of the phosphatidylinositol 3-kinase (PI3K)/Akt (protein kinase B) signaling pathway which regulates cell survival and proliferation. mTOR is a highly conserved serine/treonine kinase involved in the control of cell growth, protein synthesis, and cell cycle progression. Inhibitor of mTOR pathway have antiproliferative properties in hematological malignancies and are studied in therapeutic trials"@en . . . "Promising activity of mammalian target of rapamycin inhibitors in hematologic malignancies therapy" . "Fuchs, Ota" . . "6" . "224625" . . . "Current Signal Transduction Therapy" . "hematological malignancies; Mammalian target of rapamycin; Phosphatase and tensin homologue tumor suppressor; Phosphatidylinositol 3-kinase; Protein kinase B; TOR inhibitors"@en . "The mammalian target of rapamycin (mTOR) is a downstream mediator of the phosphatidylinositol 3-kinase (PI3K)/Akt (protein kinase B) signaling pathway which regulates cell survival and proliferation. mTOR is a highly conserved serine/treonine kinase involved in the control of cell growth, protein synthesis, and cell cycle progression. Inhibitor of mTOR pathway have antiproliferative properties in hematological malignancies and are studied in therapeutic trials" . . "Promising activity of mammalian target of rapamycin inhibitors in hematologic malignancies therapy"@en . "1"^^ . . . "11"^^ . "Promising activity of mammalian target of rapamycin inhibitors in hematologic malignancies therapy"@en . . "1574-3624" . "1"^^ . "RIV/00023736:_____/11:00009171" . . . "Promising activity of mammalian target of rapamycin inhibitors in hematologic malignancies therapy" . "http://dx.doi.org/10.2174/157436211794109460" . . . . . "[9C1791562316]" . . "P(LC06044), Z(MZ0UHKT2005)" . "1" . . . . . "RIV/00023736:_____/11:00009171!RIV12-MZ0-00023736" . "10.2174/157436211794109460" .