"P(NL7681)" . "Pluskalov\u00E1, Michaela" . "CZ - \u010Cesk\u00E1 republika" . "The tyrosine kinase activity and phosphotyrosine level were measured in mononuclear cells of chronic myelogenous leukemia (CML) patients as well as normal healthy donors. Imatinib mesylate treatment significantly reduced TK activity in parallel with the decrease of phosphotyrosine level. The change in tyrosine-kinase activity has also been observed in the healthy donors group. Imatinib mesylate probably affects cell signalization even in BCR-ABL negative cells"@en . "6"^^ . "Marinov, Iuri" . . . . . . "Hrkal, Zbyn\u011Bk" . . "Imatinib mesylate affects tyrosine kinase activity in both leukemic and normal primary mononuclear blood cells"@en . "tyrosine-kinase activity; Imatinib; K562; primary blood cells; leukemia"@en . "Imatinib mesylate affects tyrosine kinase activity in both leukemic and normal primary mononuclear blood cells"@en . . "Imatinib mesylate affects tyrosine kinase activity in both leukemic and normal primary mononuclear blood cells" . . . . . "Klamov\u00E1, Hana" . . . . "The tyrosine kinase activity and phosphotyrosine level were measured in mononuclear cells of chronic myelogenous leukemia (CML) patients as well as normal healthy donors. Imatinib mesylate treatment significantly reduced TK activity in parallel with the decrease of phosphotyrosine level. The change in tyrosine-kinase activity has also been observed in the healthy donors group. Imatinib mesylate probably affects cell signalization even in BCR-ABL negative cells" . "Imatinib mesylate affects tyrosine kinase activity in both leukemic and normal primary mononuclear blood cells" . . "RIV/00023736:_____/06:00006618!RIV07-MZ0-00023736" . "4" . "Imatinib mesylate ovliv\u0148uje tyrosin-kin\u00E1zovou aktivitu v leukemick\u00FDch i norm\u00E1ln\u00EDch prim\u00E1rn\u00EDch mononukle\u00E1rn\u00EDch krevn\u00EDch bu\u0148k\u00E1ch"@cs . "10"^^ . "Journal of Applied Biomedicine : JAB" . "Imatinib mesylate ovliv\u0148uje tyrosin-kin\u00E1zovou aktivitu v leukemick\u00FDch i norm\u00E1ln\u00EDch prim\u00E1rn\u00EDch mononukle\u00E1rn\u00EDch krevn\u00EDch bu\u0148k\u00E1ch"@cs . "2" . . . "478851" . "Marinov, Iuri" . "1214-021X" . . "Byla m\u011B\u0159ena tyrosin-kin\u00E1zov\u00E1 (TK) aktivita a hladina fosfotyrosinu mononukle\u00E1rn\u00EDch bun\u011Bk pacient\u016F s chronickou myeloidn\u00ED leuk\u00E9mi\u00ED (CML) a norm\u00E1ln\u00EDch zdrav\u00FDch d\u00E1rc\u016F. O\u0161et\u0159en\u00ED CML bun\u011Bk Imatinib mesyl\u00E1tem v\u00FDznamn\u011B sn\u00ED\u017Eilo TK aktivitu paraleln\u011B se sn\u00ED\u017Een\u00EDm hladiny fosfotyrosinu. Zm\u011Bna tyrosin-kin\u00E1zov\u00E9 aktivity byla pozorov\u00E1na t\u00E9\u017E u zdrav\u00FDch d\u00E1rc\u016F. Imatinib mesyl\u00E1t pravd\u011Bpodobn\u011B ovliv\u0148uje bun\u011B\u010Dnou signalizaci i u BCR-ABL negativn\u00EDch bun\u011Bk"@cs . "95;104" . "Grebe\u0148ov\u00E1, Dana" . "RIV/00023736:_____/06:00006618" . . "[16B37E98ADC2]" . . . "6"^^ . "Ku\u017Eelov\u00E1, Kate\u0159ina" .