. "Grebe\u0148ov\u00E1, Dana" . "Rychl\u00E1 apopt\u00F3za a erytroidn\u00ED diferenciace vyvolan\u00E9 \u00FA\u010Dinkem imatinib mesyl\u00E1tu na bun\u011B\u010Dn\u00E9 linie K 562 a JURL-MK1"@cs . "Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells."@en . . . "The effects of Imatinib mesylate on CML cell lines K562 and JURL-MK1 were compared. Imatinib mesylate arrested both cell lines in G0/G1 phase and induced apoptosis that proceeded faster in JURL-MK1 cells and occurred in larger fraction of cell population. In addition, the erythroid differentiation was triggered in both cell lines. Apoptosis and the erythroid differentiation are parallel effects of Imatinib mesylate and their relative contributions and kinetics are related to the differentiation stage of treated cells." . "Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells." . . "Imatinib mesylate;STI571;leukemia;apoptosis;erythroid differentiation"@en . "1"^^ . . "Rychl\u00E1 apopt\u00F3za a erytroidn\u00ED diferenciace vyvolan\u00E9 \u00FA\u010Dinkem imatinib mesyl\u00E1tu na bun\u011B\u010Dn\u00E9 linie K 562 a JURL-MK1"@cs . "The effects of Imatinib mesylate on CML cell lines K562 and JURL-MK1 were compared. Imatinib mesylate arrested both cell lines in G0/G1 phase and induced apoptosis that proceeded faster in JURL-MK1 cells and occurred in larger fraction of cell population. In addition, the erythroid differentiation was triggered in both cell lines. Apoptosis and the erythroid differentiation are parallel effects of Imatinib mesylate and their relative contributions and kinetics are related to the differentiation stage of treated cells."@en . "5th interdisciplinary conference mechanisms of cell death and disease : advances in therapeutic intervention and drug development" . "RIV/00023736:_____/04:I0000035" . . "36" . . "Cascais" . "Cascais" . . "3"^^ . "Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells." . "Ku\u017Eelov\u00E1, Kate\u0159ina" . "Fast apoptosis and erythroid differentiation induced by imatinib mesylate in JURL-MK1 cells."@en . "3"^^ . "[AAE7D1E3A5C0]" . . . . "P(NL7681)" . . . . "Byly porovn\u00E1ny \u00FA\u010Dinky Imatinib mesyl\u00E1tu na CML bun\u011B\u010Dn\u00E9 linie K562 a JURL-MK1. U obou lini\u00ED do\u0161lo k zastaven\u00ED bun\u011B\u010Dn\u00E9ho cyklu v G0/G1 f\u00E1zi a byla indukov\u00E1na apoptoza je\u017E u bun\u011Bk JURL-MK1 prob\u00EDhala rychleji a u v\u011Bt\u0161\u00ED \u010D\u00E1sti bun\u011B\u010Dn\u00E9 populace. D\u00E1le byla u obou lini\u00ED navozena erytroidn\u00ED diferenciace. Apoptoza a erytroidn\u00ED diferenciace jsou paraleln\u00EDmi \u00FA\u010Dinky Imatinib mesyl\u00E1tu jejich\u017E relativn\u00ED p\u0159\u00EDsp\u011Bvky a kinetiky jsou z\u00E1visl\u00E9 na diferencia\u010Dn\u00EDm stavu bun\u011Bk."@cs . . "RIV/00023736:_____/04:I0000035!RIV/2005/MZ0/L33005/N" . "Hrkal, Zbyn\u011Bk" . . . "564173" . . . "2004-10-22+02:00"^^ . . "ESH and MD Anderson Cancer Center" .