. . "10"^^ . . "P(GAP301/11/1568)" . . "CD14+Cd16+, CD14+CD163+, Kidney, Monocytes, Subpopulations, Transplantation"@en . . "15" . "6356" . . "L\u00E1nsk\u00E1, V\u011Bra" . . . . "CD14+CD16+and CD14+CD163+monocyte subpopulations in kidney allograft transplantation" . "4" . "000332972400001" . . "Krepsov\u00E1, Eva" . "Slatinsk\u00E1, Janka" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "7"^^ . . "Monocytes represent a heterogeneuos population of cells subdivided according to the expression level of membrane antigens. A pro-inflammatory (intermediate/nonclassical) subpopulation of monocytes is defined by expression of CD16. CD163 seems to be characteristically preferentially expressed by immunosuppressive monocytes.The aim of our study was to avaluete the distribution of monocyte subpopulations in 71 patients with kidney allograft transplantation. The phenotype was evaluated by flow cytometry in defined time points. The proportions of peripheral CD14+CD16+ monocytes were downregulated immediately after the kidney transplantation and basiliximab treatment partially attenuated this trend. The transient downregulation of the CD14+CD16+ subpopulation was adjust to basal values in two months. The proportions of CD14+Cd163+ monocytes were transietlyupregulated early after the kidney transplantation and remained higher during the first month in most patients. In ATG treated patients, the expansion of CD14+Cd163+ monocytes was delayd but their upregulation lasted longer." . "BMC IMMUNOLOGY" . "http://www.biomedcentral.com/1471-2172/15/4" . . "7"^^ . . . . "Viklick\u00FD, Ond\u0159ej" . . "CD14+CD16+and CD14+CD163+monocyte subpopulations in kidney allograft transplantation"@en . "[487B7DC887E3]" . "Monocytes represent a heterogeneuos population of cells subdivided according to the expression level of membrane antigens. A pro-inflammatory (intermediate/nonclassical) subpopulation of monocytes is defined by expression of CD16. CD163 seems to be characteristically preferentially expressed by immunosuppressive monocytes.The aim of our study was to avaluete the distribution of monocyte subpopulations in 71 patients with kidney allograft transplantation. The phenotype was evaluated by flow cytometry in defined time points. The proportions of peripheral CD14+CD16+ monocytes were downregulated immediately after the kidney transplantation and basiliximab treatment partially attenuated this trend. The transient downregulation of the CD14+CD16+ subpopulation was adjust to basal values in two months. The proportions of CD14+Cd163+ monocytes were transietlyupregulated early after the kidney transplantation and remained higher during the first month in most patients. In ATG treated patients, the expansion of CD14+Cd163+ monocytes was delayd but their upregulation lasted longer."@en . "RIV/00023001:_____/14:00058834" . . "CD14+CD16+and CD14+CD163+monocyte subpopulations in kidney allograft transplantation" . "RIV/00023001:_____/14:00058834!RIV15-GA0-00023001" . "Sekerkov\u00E1, Alena" . "CD14+CD16+and CD14+CD163+monocyte subpopulations in kidney allograft transplantation"@en . . . "1471-2172" . . . . "Brabcov\u00E1, Eva" . . "10.1186/1471-2172-15-4" . . "St\u0159\u00ED\u017E, Ilja" .