"Diagnostic value of postprandial triglyceride testing in healthy subjects: a meta-analysis"@en . "Mihas, Constantinos" . "Nordestgaard, Borge G" . . . "Current vascular pharmacology" . "11"^^ . "194214" . "3" . "[6A5DBC13ED32]" . "000290656600002" . "10.2174/157016111795495530" . "Ooi, Teik Chye" . "Anagnostopoulou, Katherine" . . "RIV/00023001:_____/11:00002511!RIV12-MZ0-00023001" . . . . "http://www.ingentaconnect.com/content/ben/cvp/2011/00000009/00000003/art00002?token=004e1753eae82075c5f3b3b47464c483f3b627049762f245a4f582a2f433e402c3568263c2be1e" . . . "Z(MZ0IKEM2005)" . . "AE - St\u00E1t Spojen\u00E9 arabsk\u00E9 emir\u00E1ty" . "Bilianou, Helen" . . "Background/Aim: Triglycerides (TGs) are measured in studies evaluating changes in non-fasting lipid profiles after a fat tolerance test (FTT); however, the optimal timing for TG measurements after the oral fat load is unclear. The aim of this study was to evaluate how non-fasting TG levels vary after an oral FTT in healthy subjects. Methods: This meta-analysis included 113 studies with >5 participants of Caucasian race that were indexed in PubMed from its inception through March 2010, using the search term %22postprandial lipemia%22. We only included studies that provided mean values and standard deviation (SD) (or standard error of the mean) for TG measurements at baseline (=fasting) and for at least one other time-point. Exclusion criteria included uncommon sampling time-points after the FTT, baseline TGs >= 2.0 mmol/L (>= 177mg/dl), and a body mass index >= 30kg/m(2). Results: All studies combined, weighted mean +/- SD TG values in mmol/L were 1.25 +/- 0.32 fasting, 1.82 +/- 0.40 at 2 h, 2.31 +/- 0.62 at 4 h, 1.87 +/- 0.63 at 6 h, and 1.69 +/- 0.80 at 8 h. After stratifying studies based on fat quantity in the test meal (<40, >= 40-<50, >= 50-<60, <60-<70, >= 70-<80, >= 80-<90, >= 90-<100,>= 100-<110, >= 110-120, >= 120 g), the highest standardized mean difference in TG levels from fasting levels was found in those having an oral fat load of >= 70 g and <80 g, and at 4 h (difference=1.74 mmol/L; p<0.001). Conclusion: The 4 h time-point after an oral fat load during a FTT was the most representative measurement of TGs. The highest standardized mean difference of TGs was found after a meal containing 70-79g of fat. The relevance of these two key parameters determined in healthy subjects should be considered for further developments of an oral FFT for clinical purposes." . . . . . . "Fat tolerance test; meta-analysis; postprandial lipaemia; standardized mean difference; triglycerides"@en . "RIV/00023001:_____/11:00002511" . "Panotopoulos, George" . "Kolovou, Genovefa D" . "Kov\u00E1\u0159, Jan" . "Background/Aim: Triglycerides (TGs) are measured in studies evaluating changes in non-fasting lipid profiles after a fat tolerance test (FTT); however, the optimal timing for TG measurements after the oral fat load is unclear. The aim of this study was to evaluate how non-fasting TG levels vary after an oral FTT in healthy subjects. Methods: This meta-analysis included 113 studies with >5 participants of Caucasian race that were indexed in PubMed from its inception through March 2010, using the search term %22postprandial lipemia%22. We only included studies that provided mean values and standard deviation (SD) (or standard error of the mean) for TG measurements at baseline (=fasting) and for at least one other time-point. Exclusion criteria included uncommon sampling time-points after the FTT, baseline TGs >= 2.0 mmol/L (>= 177mg/dl), and a body mass index >= 30kg/m(2). Results: All studies combined, weighted mean +/- SD TG values in mmol/L were 1.25 +/- 0.32 fasting, 1.82 +/- 0.40 at 2 h, 2.31 +/- 0.62 at 4 h, 1.87 +/- 0.63 at 6 h, and 1.69 +/- 0.80 at 8 h. After stratifying studies based on fat quantity in the test meal (<40, >= 40-<50, >= 50-<60, <60-<70, >= 70-<80, >= 80-<90, >= 90-<100,>= 100-<110, >= 110-120, >= 120 g), the highest standardized mean difference in TG levels from fasting levels was found in those having an oral fat load of >= 70 g and <80 g, and at 4 h (difference=1.74 mmol/L; p<0.001). Conclusion: The 4 h time-point after an oral fat load during a FTT was the most representative measurement of TGs. The highest standardized mean difference of TGs was found after a meal containing 70-79g of fat. The relevance of these two key parameters determined in healthy subjects should be considered for further developments of an oral FFT for clinical purposes."@en . "Diagnostic value of postprandial triglyceride testing in healthy subjects: a meta-analysis" . "9" . "10"^^ . "1"^^ . "1570-1611" . "Lairon, Dennis" . "Diagnostic value of postprandial triglyceride testing in healthy subjects: a meta-analysis" . . "Mikhailidis, Dimitri P" . . "Perez-Martinez, Pablo" . "Diagnostic value of postprandial triglyceride testing in healthy subjects: a meta-analysis"@en . .