"Trune\u010Dka, Pavel" . "P(NS9707), P(NT11238), Z(MZ0IKEM2005)" . "000295177400005" . "0968-5243" . . . . . "Magnetic resonance materials in physics, biology and medicine" . "RIV/00023001:_____/11:00002472" . "5" . "Hejlov\u00E1, Irena" . . . . "10.1007/s10334-011-0264-9" . "RIV/00023001:_____/11:00002472!RIV12-MZ0-00023001" . "DE - Spolkov\u00E1 republika N\u011Bmecko" . . "24" . "Dezortov\u00E1, Monika" . . . "214130" . "Wagnerov\u00E1, Dita" . . "MR spectroscopy as a tool for in vivo determination of steatosis in liver transplant recipients"@en . "8"^^ . . "Voska, Lud\u011Bk" . . . "Among several non-invasive methods of liver fat analysis, the most important role is played by MR imaging and spectroscopy (MRS). This study describes the 1H MRS at 3T measurement of liver fat volume fraction fat in a group of liver transplant patients, an at-risk group for the development of de novo steatosis. Linear and non-linear regression models were used to describe the relationship between fat and His. Strong correlation was found for both models with r =0.83-0.94 (p<0.001); a higher r was found for non-linear regression in all tested groups. Areas under receiver operation curves were calculated for cut points His >= 5% and >33% and were found in the range of 0.77-0.86. Fibrosis influences the calculation of fat and different slopes were obtained for fibrosis stage F0-F1 and F2-F3, respectively. Significant correlation was found between the results of histology and 1H MRS measurement of liver fat content. The method is suitable for non-invasive repetitive examination of liver fat in liver-transplants patients between protocol biopsies and for the screening of steatosis in other liver diseases."@en . . . . "\u0160koch, Anton\u00EDn" . "7"^^ . "MR spectroscopy as a tool for in vivo determination of steatosis in liver transplant recipients" . "Among several non-invasive methods of liver fat analysis, the most important role is played by MR imaging and spectroscopy (MRS). This study describes the 1H MRS at 3T measurement of liver fat volume fraction fat in a group of liver transplant patients, an at-risk group for the development of de novo steatosis. Linear and non-linear regression models were used to describe the relationship between fat and His. Strong correlation was found for both models with r =0.83-0.94 (p<0.001); a higher r was found for non-linear regression in all tested groups. Areas under receiver operation curves were calculated for cut points His >= 5% and >33% and were found in the range of 0.77-0.86. Fibrosis influences the calculation of fat and different slopes were obtained for fibrosis stage F0-F1 and F2-F3, respectively. Significant correlation was found between the results of histology and 1H MRS measurement of liver fat content. The method is suitable for non-invasive repetitive examination of liver fat in liver-transplants patients between protocol biopsies and for the screening of steatosis in other liver diseases." . "biopsy; lipids; liver steatosis; liver transplantation; magnetic resonance spectroscopy"@en . . . . . . "7"^^ . . . . "MR spectroscopy as a tool for in vivo determination of steatosis in liver transplant recipients"@en . . . "H\u00E1jek, Milan" . "[71392683B5F9]" . "MR spectroscopy as a tool for in vivo determination of steatosis in liver transplant recipients" .