. "1"^^ . . "P(NS9743), V, Z(MSM0021620819), Z(MSM0021620820)" . "9" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "RIV/00023001:_____/10:00002365" . "Objectives: Difficulty healing wounds and skin defects is a frequent problem in patients on chronic hemodialysis (HD) because of malnutrition, inflammation, and atherosclerosis (MIA) syndrome. The aim of the present study was to estimate the influence of peripheral blood flow changes during HD on the development of foot defects and its relationship to plasma albumin levels. Methods: Peripheral skin blood flow was measured using a laser Doppler line scanner in 10 different areas of the dorsal part of the instep and the toes of each foot before and during HD with ultrafiltration (897 465 mL/procedure) in 31 HD patients (10 female, 21 male; age 36-79 y, body mass index 28 5.0). No skin defects or apparent acute disease or infection were detected in any patient at the time of laser Doppler line scanner measurement. The feet of the patients were clinically re-examined carefully over the next 18 mo. Results: We found a significant and constant decrease of skin blood flow during the HD procedure (P" . "26" . "4"^^ . "Plasma albumin levels correlate with decreased microcirculation and the development of skin defects in hemodialyzed patients"@en . . "Plasma albumin levels correlate with decreased microcirculation and the development of skin defects in hemodialyzed patients"@en . . "[F720D5D66DD8]" . "RIV/00023001:_____/10:00002365!RIV11-MZ0-00023001" . "Sobotka, L." . . "Malnutrition; Inflammation; Skin wounds; Skin blood flow; Hemodialysis"@en . . "Bl\u00E1ha, V." . "000280925200008" . "0899-9007" . . . . . . "Plasma albumin levels correlate with decreased microcirculation and the development of skin defects in hemodialyzed patients" . "Dusilov\u00E1 - Sulkov\u00E1, Sylvie" . "6"^^ . . "Plasma albumin levels correlate with decreased microcirculation and the development of skin defects in hemodialyzed patients" . "Objectives: Difficulty healing wounds and skin defects is a frequent problem in patients on chronic hemodialysis (HD) because of malnutrition, inflammation, and atherosclerosis (MIA) syndrome. The aim of the present study was to estimate the influence of peripheral blood flow changes during HD on the development of foot defects and its relationship to plasma albumin levels. Methods: Peripheral skin blood flow was measured using a laser Doppler line scanner in 10 different areas of the dorsal part of the instep and the toes of each foot before and during HD with ultrafiltration (897 465 mL/procedure) in 31 HD patients (10 female, 21 male; age 36-79 y, body mass index 28 5.0). No skin defects or apparent acute disease or infection were detected in any patient at the time of laser Doppler line scanner measurement. The feet of the patients were clinically re-examined carefully over the next 18 mo. Results: We found a significant and constant decrease of skin blood flow during the HD procedure (P"@en . "Nutrition" . . . . . . . . . "279104" . "Mistr\u00EDk, E." . .