"Pelouch, R." . "1"^^ . "Background and aim of the study: Limited data have been reported that characterize infective endocarditis (IE) in the Czech Republic. Hence, some local cases of IE were examined to provide a current profile of the disease in Central Europe. Methods: A descriptive case series of IE patients seen on all internal medicine services of a major teaching institution in the Czech Republic over an eight-year period was developed. Results: Prosthetic valves and rheumatic carditis were the underlying predisposing conditions in 18% and 17%, respectively, of all IE episodes. Staphylococcal species were the most common pathogens identified, and were present in 45% of IE episodes. In contrast, streptococcal species were recovered in only 14% of episodes. The proportion of culture-negative endocarditis cases was sizable (18%). The aortic valve was most commonly involved in IE episodes (47%), followed by the mitral valve (33%). The in-hospital mortality rate was 21%. Conclusion: Younger patients, the occurren"@en . "Baddour, L. M." . . "[0B91270653CE]" . . . "3"^^ . "RIV/00023001:_____/09:00002119" . "RIV/00023001:_____/09:00002119!RIV10-MZ0-00023001" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "Infective endocarditis in the Czech republic: eight years of experience at one of the country's largest medical centers" . . "Journal of heart valve disease" . . . "18" . . "Infective endocarditis in the Czech republic: eight years of experience at one of the country's largest medical centers" . "6"^^ . . . "0966-8519" . "Infective endocarditis in the Czech republic: eight years of experience at one of the country's largest medical centers"@en . "infective endocarditis; Czech republic"@en . "Background and aim of the study: Limited data have been reported that characterize infective endocarditis (IE) in the Czech Republic. Hence, some local cases of IE were examined to provide a current profile of the disease in Central Europe. Methods: A descriptive case series of IE patients seen on all internal medicine services of a major teaching institution in the Czech Republic over an eight-year period was developed. Results: Prosthetic valves and rheumatic carditis were the underlying predisposing conditions in 18% and 17%, respectively, of all IE episodes. Staphylococcal species were the most common pathogens identified, and were present in 45% of IE episodes. In contrast, streptococcal species were recovered in only 14% of episodes. The proportion of culture-negative endocarditis cases was sizable (18%). The aortic valve was most commonly involved in IE episodes (47%), followed by the mitral valve (33%). The in-hospital mortality rate was 21%. Conclusion: Younger patients, the occurren" . "319100" . . "000268746300007" . "Infective endocarditis in the Czech republic: eight years of experience at one of the country's largest medical centers"@en . "4" . "N, V" . "Pazdern\u00EDk, Michal" . . . . .