. "Kontrola frekvence nebo komorov\u00E9ho rytmu v l\u00E9\u010Db\u011B fibrilace s\u00EDn\u00ED" . "RIV/00023001:_____/07:00001526" . "N" . "Rate or rhythm control in the treatment of atrial fibrillation"@en . . . "1214-2255" . "Kardiof\u00F3rum" . . "1"^^ . . . "Kautzner, Josef" . . "CZ - \u010Cesk\u00E1 republika" . "V sou\u010Dasn\u00E9 dob\u011B existuj\u00ED data z randomizovan\u00FDch klinick\u00FDch studi\u00ED, kter\u00E9 porovn\u00E1valy 2 strategie l\u00E9\u010Dby FiS: snahu o udr\u017Een\u00ED sinusov\u00E9ho rytmu pomoc\u00ED antiarytmik se strategi\u00ED zam\u011B\u0159enou na kontrolu frekvence komor, p\u0159ev\u00E1\u017En\u011B za pomoc\u00ED l\u00E9k\u016F zpomaluj\u00EDc\u00EDch s\u00ED\u0148okomorov\u00FD p\u0159evod. V\u00FDsledky uk\u00E1zaly, \u017Ee ob\u011B strategie jsou rovnocenn\u00E9 co do vlivu na progn\u00F3zu nemocn\u00FDch. Na druh\u00E9 stran\u011B to neznamen\u00E1, \u017Ee ponech\u00E1n\u00ED fibrilace s\u00EDn\u00ED je obecn\u011B srovnateln\u00E9 s udr\u017Een\u00EDm sinusov\u00E9ho rytmu. Anal\u00FDza studi\u00ED nazna\u010Dila, \u017Ee se t\u00FDkaj\u00ED zhruba 50 % populace nemocn\u00FDch s FiS, a to sp\u00ED\u0161e z vy\u0161\u0161\u00EDch v\u011Bkov\u00FDch skupin, bez projev\u016F srde\u010Dn\u00EDho selh\u00E1n\u00ED a s riziky tromboembolizmu. Krom\u011B toho existuj\u00ED podskupiny pacient\u016F, kter\u00E9 mohou z\u0159eteln\u011B benefitovat z kontroly rytmu pomoc\u00ED antiarytmik. Vedle toho se dnes rozv\u00EDjej\u00ED i nefarmakologick\u00E9 l\u00E9\u010Debn\u00E9 postupy zam\u011B\u0159en\u00E9 na odstran\u011Bn\u00ED arytmie. V mnoha centrech je lze ji\u017E pova\u017Eovat za standardn\u00ED l\u00E9\u010Dbu, jej\u00ED\u017E \u00FA\u010Dinnost se pohybuje mezi 65?90 %, podle charakteru FiS, v\u00FDskytu strukturn\u00EDho onemocn\u011Bn\u00ED srdce nebo pou\u017Ei" . "1"^^ . . "There are data currently available from randomised clinical studies comparing 2 different strategies of AF treatment: effort to maintain sinus rhythm with antiarrhythmic drugs, and rate control, using drugs that slow down atrioventricular conduction. Results have shown that both the strategies are of equal value in terms of the way they effect patients? prognosis. This, however, does not mean that maintaining atrial fibrillation is generally comparable with the preservation of sinus rhythm. Analysis of studies indicates that these only refer to approximately 50% of AF patients most of whom are of higher age groups, without symptoms of heart failure and with the risk of thromboembolism. In addition, there are subgroups of patients who can largely benefit from rhythm control with antiarrhythmic drugs. Beside this, non-pharmacological methods of treatment are under development, focusing on elimination of arrhythmia. These have become standard methods of therapy in many centres, and their success rates ra"@en . . "RIV/00023001:_____/07:00001526!RIV08-MZ0-00023001" . . "1" . "Kontrola frekvence nebo komorov\u00E9ho rytmu v l\u00E9\u010Db\u011B fibrilace s\u00EDn\u00ED" . . "atrial fibrillation; antiarrhytmics drugs; catheter ablation; thromboembolism"@en . "5" . . "[938D707D9CF4]" . "429747" . . "11-15" . . "V sou\u010Dasn\u00E9 dob\u011B existuj\u00ED data z randomizovan\u00FDch klinick\u00FDch studi\u00ED, kter\u00E9 porovn\u00E1valy 2 strategie l\u00E9\u010Dby FiS: snahu o udr\u017Een\u00ED sinusov\u00E9ho rytmu pomoc\u00ED antiarytmik se strategi\u00ED zam\u011B\u0159enou na kontrolu frekvence komor, p\u0159ev\u00E1\u017En\u011B za pomoc\u00ED l\u00E9k\u016F zpomaluj\u00EDc\u00EDch s\u00ED\u0148okomorov\u00FD p\u0159evod. V\u00FDsledky uk\u00E1zaly, \u017Ee ob\u011B strategie jsou rovnocenn\u00E9 co do vlivu na progn\u00F3zu nemocn\u00FDch. Na druh\u00E9 stran\u011B to neznamen\u00E1, \u017Ee ponech\u00E1n\u00ED fibrilace s\u00EDn\u00ED je obecn\u011B srovnateln\u00E9 s udr\u017Een\u00EDm sinusov\u00E9ho rytmu. Anal\u00FDza studi\u00ED nazna\u010Dila, \u017Ee se t\u00FDkaj\u00ED zhruba 50 % populace nemocn\u00FDch s FiS, a to sp\u00ED\u0161e z vy\u0161\u0161\u00EDch v\u011Bkov\u00FDch skupin, bez projev\u016F srde\u010Dn\u00EDho selh\u00E1n\u00ED a s riziky tromboembolizmu. Krom\u011B toho existuj\u00ED podskupiny pacient\u016F, kter\u00E9 mohou z\u0159eteln\u011B benefitovat z kontroly rytmu pomoc\u00ED antiarytmik. Vedle toho se dnes rozv\u00EDjej\u00ED i nefarmakologick\u00E9 l\u00E9\u010Debn\u00E9 postupy zam\u011B\u0159en\u00E9 na odstran\u011Bn\u00ED arytmie. V mnoha centrech je lze ji\u017E pova\u017Eovat za standardn\u00ED l\u00E9\u010Dbu, jej\u00ED\u017E \u00FA\u010Dinnost se pohybuje mezi 65?90 %, podle charakteru FiS, v\u00FDskytu strukturn\u00EDho onemocn\u011Bn\u00ED srdce nebo pou\u017Ei"@cs . . "Kontrola frekvence nebo komorov\u00E9ho rytmu v l\u00E9\u010Db\u011B fibrilace s\u00EDn\u00ED"@cs . "Rate or rhythm control in the treatment of atrial fibrillation"@en . "Kontrola frekvence nebo komorov\u00E9ho rytmu v l\u00E9\u010Db\u011B fibrilace s\u00EDn\u00ED"@cs . "5"^^ .