"The subject of the proposal is to create Laboratory of Biomolecular Structure and Dynamics. An efficient scientific program is proposed, which will ensure that two recent large investment activities (the supercomputer project and the NMR instrument) willefficiently be used. The project is a combination of NMR spectroscopy, X-ray crystallography and computer modeling. The scientific goals include both methodoly development and its applications on biologically interesting molecules. The systems studied will include oligonucleotides, peptides, carbohydrates, nucleotide-sugars, and proteins. The strategical direction for high technology will be biodegradation in the environment."@en . "biomolecular structure and dynamics" . " NMR spectroscopy" . . . . "Laborato\u0159 struktury a dynamiky biomolekul, kter\u00E1 je kompozic\u00ED \u010Dty\u0159 v\u00FDzk. skupin v\u00A0oblastech NMR spektroskopie biomolekul, po\u010D\u00EDta\u010D. modelov\u00E1n\u00ED a simulac\u00ED biomolekul, protein. in\u017Een\u00FDrstv\u00ED dehalogen\u00E1z a rentg. krystalografie biomolekul zahrnuj\u00EDce proteiny."@cs . "0"^^ . . "biomolecular structure and dynamics, structural biology, computer modeling, NMR spectroscopy, X-ray"@en . . "1"^^ . "Laborato\u0159 struktury a dynamiky biomolekul" . "Laboratory of Structure and Dynamics of Biomolecules"@en . . "0"^^ . . . "P\u0159edm\u011Btem projektu je vytvo\u0159en\u00ED laborato\u0159e struktury a dynamiky biomolekul. Z\u00E1kladn\u00ED metodika obn\u00E1\u0161\u00ED: NMR spektroskopii, rentgenovou difrakci, po\u010D\u00EDta\u010Dovou chemii a molekulov\u00E9 modelov\u00E1n\u00ED. P\u0159edm\u011Btem studia jsou jak mal\u00E9 a st\u0159edn\u00ED biomolekuly (oligonukleotidy, cukry), tak biopolymery (proteiny)." . . . " structural biology" . . " computer modeling" . "41"^^ . . "http://www.isvav.cz/projectDetail.do?rowId=VS96095"^^ . . . "41"^^ . "VS96095" . .