"14"^^ . . "14"^^ . . . . . "http://www.isvav.cz/projectDetail.do?rowId=TA01010436"^^ . . . "The Commission notes that results were achieved in accordance with the contract/amendment. According to the presentation one of the results is prepared for commercial use. The use of other results is described in the contract of use of the results."@en . "Komise konstatuje, \u017Ee bylo dosa\u017Eeno v\u00FDsledk\u016F v souladu se Smlouvou/dodatkem. Dle prezentace je jeden z v\u00FDsledk\u016F p\u0159ipraven pro komer\u010Dn\u00ED vyu\u017Eit\u00ED. K vyu\u017Eit\u00ED ostatn\u00EDch v\u00FDsledk\u016F sm\u011B\u0159uje smlouva o vyu\u017Eit\u00ED v\u00FDsledk\u016F."@cs . "New generations of DNA aptamers"@en . "TA01010436" . . "2013-02-28+01:00"^^ . "The aim of this project is to design new technologies for production of oligonucleotide DNA aptamers and to prepare DNA aptamers which could be used, after finalization, for commercial purposes. Specifically, aptamers suitable for isolation of temperature-resistant Taq DNA polymerase, for hot-start PCR, for identification of highly conserved cytoskeletal components (neurofilaments and betaIII tubulin) and small organic molecules (specified in section 2.3). Selected small organic molecules will be used as models with the aim to develop universal technologies for detection of such substances by DNA aptamers in a highly simplified manner. In this way it should be possible to allow variable immobilization of target molecules and thus designing multipurpose chips. Such antibody-free testing sets will be suitable for commercial purposes."@en . . "2011-01-01+01:00"^^ . . . . "Nov\u00E9 generace DNA aptamer\u016F" . . . . "C\u00EDlem tohoto projektu je navrhnout nov\u00E9 technologie p\u0159\u00EDpravy oligonukleotidov\u00FDch DNA aptamer\u016F a p\u0159ipravit aptamery, kter\u00E9 by mohly b\u00FDt vyu\u017Eiteln\u00E9 (po fin\u00E1ln\u00EDm dopracov\u00E1n\u00ED) ke komer\u010Dn\u00EDm \u00FA\u010Del\u016Fm. Konkr\u00E9tn\u011B se jedn\u00E1 o aptamery vyu\u017Eiteln\u00E9 pro izolaci teplotn\u011B-rezistentn\u00ED Taq DNA polymer\u00E1zy, pro hot-start PCR, pro identifikaci konzervativn\u00EDch komponent cytoskeletu (neurofilamenta a beta III tubulin) a mal\u00FDch molekul. V oboru mal\u00FDch organick\u00FDch molekul budou konkr\u00E9tn\u00ED l\u00E1tky (vyjmenovan\u00E9 v \u010D\u00E1sti 2.3.) vyu\u017E\u00EDv\u00E1ny pouze jako modely, c\u00EDlem je v\u00FDvoj univerz\u00E1ln\u00ED technologie pro detekci t\u011Bchto l\u00E1tek pomoc\u00ED aptamer\u016F ve velmi jednoduch\u00E9m uspo\u0159\u00E1d\u00E1n\u00ED, umo\u017E\u0148uj\u00EDc\u00EDm tak\u00E9 variabiln\u00ED imobilizaci rozpozn\u00E1vac\u00ED molekuly a t\u00EDm sestaven\u00ED v\u00EDce\u00FA\u010Delov\u00E9ho \u010Dipu. Takto uspo\u0159\u00E1dan\u00E9 testovac\u00ED soupravy nepou\u017E\u00EDvaj\u00EDc\u00ED protil\u00E1tky budou pou\u017Eiteln\u00E9 ke komer\u010Dn\u00EDm \u00FA\u010Del\u016Fm." . . "1"^^ . "2"^^ . . . "DNA aptamers" . " antibodies" . . "0"^^ . . "2015-05-26+02:00"^^ . "DNA aptamers; antibodies; amplification"@en . "2013-12-31+01:00"^^ .