. . "V\u00FDsledky z\u00EDskan\u00E9 v projektu AIRGEN jsou zcela unik\u00E1tn\u00ED, je to v\u016Fbec poprv\u00E9 v \u010Cesk\u00E9 republice, kdy bylo pou\u017Eito tak \u0161irok\u00E9ho spektra metod, v\u010Detn\u011B nov\u00FDch metod genomiky, kter\u00E9 p\u0159in\u00E1\u0161ej\u00ED nov\u00E9 informace o z\u00E1va\u017Enosti expozic vysoce zne\u010Di\u0161t\u011Bn\u00E9mu ovzdu\u0161\u00ED a o jejich d\u016Fsledc\u00EDch pro lidsk\u00E9 zdrav\u00ED."@cs . "Z\u00EDsk\u00E1n\u00ED nov\u00FDch poznatk\u016F o p\u016Fsoben\u00ED komplexn\u00EDch sm\u011Bs\u00ED l\u00E1tek v\u00E1zan\u00FDch na prachov\u00E9 \u010D\u00E1stice (k-PAU, toxick\u00E9 kovy) a VOC v ovzdu\u0161\u00ED na lidsk\u00FDch organismus. Na r\u016Fzn\u00FDch populac\u00EDch na Ostravsku (d\u011Bti, str\u00E1\u017En\u00EDci) budou studov\u00E1ny mechanismy p\u016Fsoben\u00ED t\u011Bchto l\u00E1tek na lidsk\u00FD genom (genov\u00E1 exprese, genetick\u00E9 polymorfismy)." . "air pollution; carcinogenic PAHs; PM10; PM2.5; children\u00B4s morbidity; asthma; gene expression; DNA adducts; genotypes; biochips; oxidative stress; smoking; molecular epidemiology"@en . . "SP/1B3/8/08" . . " asthma" . "2010-04-08+02:00"^^ . . "0"^^ . " genotypes" . "2008-07-01+02:00"^^ . . . "2010-12-31+01:00"^^ . . "1"^^ . . . . "0"^^ . . . " children\u00B4s morbidity" . " gene expression" . . "Studium zdravotn\u00EDch d\u016Fsledk\u016F zne\u010Di\u0161t\u011Bn\u00E9ho ovzdu\u0161\u00ED na Ostravsku s vyu\u017Eit\u00EDm genomiky -AIRGEN" . "2011-06-30+02:00"^^ . " DNA adducts" . " smoking" . "air pollution" . . . " PM2.5" . "The impact of air pollution to human health in the Ostrava region using genomic methods - AIRGEN"@en . " oxidative stress" . . "27"^^ . " PM10" . . "27"^^ . "To obtain new knowledge on the effects of complex mixtures bound to dust particles (c-PAHs, toxic metals) and VOC in the ambient air on humans. The mechanisms of the action of these compounds on the human genome (gene expression, genetic polymorphisms) will be studied in different populations (children, city policemen) from the Ostrava region."@en . " biochips" . "http://www.isvav.cz/projectDetail.do?rowId=SP/1B3/8/08"^^ . " carcinogenic PAHs" . . "Results obtained in the project AIRGEN are very unique. It is already for the first time in the Czech Republic, when such a broad spectrum of molecular epidemiology methods were used. New information indicate the significance of the air pollution to human health."@en .