. . . . . " Therapy" . . . "V pr\u016Fb\u011Bhu projektu byla pro genovou diagnostiku zavedena a optimalizov\u00E1na \u0159ada modern\u00EDch technik. Dosa\u017Een\u00E9 v\u00FDsledky bude mo\u017Eno vyu\u017E\u00EDt k podrobn\u011Bj\u0161\u00ED genetick\u00E9 subklasifikaci n\u00E1doru, jeho l\u00E9\u010Db\u011B a predikci."@cs . "2007-05-31+02:00"^^ . . . "0"^^ . . "In the project advanced techniques of gene diagnostics were introduced and optimized. Results can be used for a more detailed genetic sub-classification of tumour, its treatment and prediction"@en . "0"^^ . . . "1"^^ . "http://www.isvav.cz/projectDetail.do?rowId=OC B19.001"^^ . . . "The substance of the project consists in a precise selective removal of tumor tissue from different parts of the brain tumor by means of computer-navigated stereotaxis, and subsequent molecular-genetic processing of samples of tumor tissue.The aim is to obtain data on the types of genetic abnormalities from different parts of multiform glioblastoma, and to acquire new knowledge that could be used in its treatment. Another aim of the project is to develop and apply newmethods and technologies (e.g. FISH # fluorescence in-situ hybridization, CGH # comparative genomic hybridization) employed in the detection of structural and numerical defects of chromosomes in the solution of problems of GBM.A special point of the study will be the correlation between deletions, hyperdiploid or amplification types and translocations of genetic material, and the prognostic significance of these specific findings in GBM."@en . . . "Podstatou projektu je selektivn\u00ED odb\u011Br tk\u00E1n\u011B miltiformn\u00EDho glioblastomu pomoc\u00ED po\u010Dita\u010Dem navigovan\u00E9 stereotaxe a n\u00E1sledn\u00E9 molekul\u00E1rn\u011B genetick\u00E9 zpracov\u00E1n\u00ED n\u00E1dorov\u00E9 tk\u00E1n\u011B s c\u00EDlem z\u00EDskat nov\u00E9 poznatky vyu\u017Eiteln\u00E9 p\u0159i jeho l\u00E9\u010Den\u00ED." . "Gene Diagnostics, Therapy, Multiform Glioblastoma"@en . . "Gene Diagnostics and Therapy of Multiform Glioblastoma"@en . "Genov\u00E1 diagnostika a terapie multiformn\u00EDho glioblastomu" . "20"^^ . "Gene Diagnostics" . "OC B19.001" . . . "20"^^ . .