. . . . . "Bradykineze (pohybov\u00E9 zpomalen\u00ED) je vedouc\u00EDm p\u0159\u00EDznakem Parkinsonovy nemoci (PN), kl\u00ED\u010Dov\u00FDm pro diagn\u00F3zu a pro odhad funk\u010Dn\u00EDho posti\u017Een\u00ED pacient\u016F. Typick\u00FDm projevem bradykineze u PN je postupn\u00FD pokles amplitudy, zpomalov\u00E1n\u00ED a nepravidelnost repetitivn\u00EDch pohyb\u016F v \u010Dase. Pro hodnocen\u00ED v praxi jsou v\u0161ak k disposici pouze klinick\u00E9 stupnice (nej\u010Dast\u011Bji tzv. UPDRS) zalo\u017Een\u00E9 na odhadu t\u00ED\u017Ee bradykineze na ordin\u00E1ln\u00ED \u0161k\u00E1le. Tak v\u0161ak nelze postihnout jemn\u011Bj\u0161\u00ED rozd\u00EDly v t\u00ED\u017Ei bradykineze a jej\u00ED zm\u011Bny v \u010Dase. Proto byl ve spolupr\u00E1ci navrhovatelsk\u00FDch pracovi\u0161\u0165 vyvinut kamerov\u00FD syst\u00E9m BradykAn pro registraci a anal\u00FDzu pohyb\u016F horn\u00ED kon\u010Detiny. C\u00EDlem grantov\u00E9ho projektu je validovat syst\u00E9m ve srovn\u00E1n\u00ED s dal\u0161\u00EDmi metodami a ov\u011B\u0159it jeho vyu\u017Eitelnost v diferenci\u00E1ln\u00ED diagnostice PN a p\u0159i monitorov\u00E1n\u00ED bradykineze v\u010Detn\u011B odpov\u011Bdi na l\u00E9\u010Dbu. Dal\u0161\u00EDm c\u00EDlem je studium vztah\u016F bradykineze a dal\u0161\u00EDch parametr\u016F poruchy hybnosti k typick\u00E9 poru\u0161e \u0159e\u010Di u PN (hypokinetick\u00E9 dysartrii) a jej\u00EDm d\u00EDl\u010D\u00EDm charakteristik\u00E1m dle akustick\u00E9 anal\u00FDzy." . "3"^^ . "NT14181" . . "3"^^ . "2014-03-21+01:00"^^ . . "1"^^ . "Analysis of bradykinesia and speech in Parkinson\u2019s disease"@en . . "Anal\u00FDza bradykineze a poruch \u0159e\u010Di u Parkinsonovy nemoci" . . " finger tapping" . "1"^^ . "2015-01-22+01:00"^^ . . . "0"^^ . . . . "Bradykinesia is the leading motor symptom of Parkinson\u2019s disease (PD), and is crucial for diagnosis and for estimation of the patient\u2019s functional deficit. Bradykinesia is generally described as reduction of amplitude, slowing down and irregularity of movements. In practice, bradykinesia is assessed using ordinal rating scales (most often, the UPDRS) that however hardly discriminate delicate differences in the severity of bradykinesia and its temporal changes. Therefore, BradykAn system has been developed for analysis of upper limb movements. The present project aims to validate the BradykAn system in comparison with other tests, and to verify its applicability in differential diagnosis of hypokinetic movement disorders and in monitoring of bradykinesia severity, including the effects of treatment. Another goal is to study the relationship between bradykinesia and hypokinetic dysartria, the characteristic speech problem in PD, as measured using advanced methods of acoustic analysis."@en . . "2015-12-31+01:00"^^ . "Parkinson's disease" . . . "http://www.isvav.cz/projectDetail.do?rowId=NT14181"^^ . " bradykinesia" . "2013-05-01+02:00"^^ . "Parkinson's disease; bradykinesia; finger tapping; hypokinetic dysarthria"@en .