"2015-12-31+01:00"^^ . . "NT13465" . "1"^^ . "atopic dermatitis; topical treatment; quality of life"@en . . "0"^^ . "1"^^ . "2014-03-21+01:00"^^ . "0"^^ . . . "atopic dermatitis" . . . . "Influence of the topical treatment on the quality of life of patients with atopic dermatitis"@en . . " topical treatment" . . . "C\u00EDlem na\u0161eho projektu je zjistit, zda AD m\u00E1 vliv na kvalitu \u017Eivota pacient\u016F a jak\u00FD vliv m\u00E1 spr\u00E1vn\u011B aplikov\u00E1na m\u00EDstn\u00ED l\u00E9\u010Dba na kvalitu \u017Eivota pacient\u016F. Dal\u0161\u00EDm c\u00EDlem je vyhodnotit vliv lok\u00E1ln\u00EDch prepar\u00E1t\u016F pou\u017E\u00EDvan\u00FDch v terapii AD, porovnat jejich ne\u017E\u00E1douc\u00ED \u00FA\u010Dinky, vliv na stav k\u016F\u017Ee (struktur\u00E1ln\u00ED zm\u011Bny k\u016F\u017Ee, atrofie k\u016F\u017Ee) a vypracovat doporu\u010Den\u00FD postup l\u00E9\u010Dby AD pro l\u00E9ka\u0159e zohled\u0148uj\u00EDc\u00ED kvalitu \u017Eivota a vydat doporu\u010Den\u00ED pro pacienty a jejich rodiny. Dosud v \u010CR nebyla provedena studie, kter\u00E1 by posuzovala jak\u00FDkoliv z aspekt\u016F na\u0161eho projektu. Pacienti budou vy\u0161et\u0159eni klinicky, stav k\u016F\u017Ee bude hodnocen pomoc\u00ED vy\u0161et\u0159en\u00ED k\u016F\u017Ee konfok\u00E1ln\u00EDm mikroskopem a kvalita \u017Eivota bude hodnocena pomoc\u00ED validovan\u00FDch dotazn\u00EDk\u016F. Pacienti budou randomizov\u00E1ni a l\u00E9\u010Deni dle dvou doporu\u010Den\u00FDch postup\u016F. Data budou zpracov\u00E1na a vyhodnocena. Pou\u017Eit\u00ED konfok\u00E1ln\u00EDho mikroskopu je novou vy\u0161et\u0159ovac\u00ED metodou zhodnocen\u00ED stavu k\u016F\u017Ee in vivo, kter\u00E1 je objektivn\u00ED a lze ji vyu\u017E\u00EDt k hodnocen\u00ED efektu zaveden\u00E9 m\u00EDstn\u00ED terapie." . "http://www.isvav.cz/projectDetail.do?rowId=NT13465"^^ . . . . "Vliv lok\u00E1ln\u00ED terapie na kvalitu \u017Eivota pacient\u016F s atopickou dermatitidou" . "The main aim of our project is to find out if AD has any effect on the quality of life of patients suffering with this disease and in case of children on their families. To find out what influence has the topical treatment on the quality of life of patients with AD. Then to evaluate the topical treatment used in AD, compare their side effects and influence on the skin (structural changes of the skin, atrophy of the skin). Finally we would like to create the recommended scheme of treatment of AD which will be considering and including the influence of the disease on the quality of life, giving the patients and their parents the treatment recommendations' protocols. In the Czech Republic no study has been conducted about any aspect of this topic so far. The patients will be examined physically, the state of the skin will be determined by the examination with the confocal microscopy and the quality of life will be assumed by the validated questionnaires."@en . "2012-04-01+02:00"^^ . . "2015-01-22+01:00"^^ . "0"^^ . . . .