. . . . . "MiR137 a jej\u00ED vliv na produkci mucin\u016F jako potenci\u00E1ln\u00ED marker pro \u010Dasnou diagn\u00F3zu kolorekt\u00E1ln\u00EDho karcinomu \u010Di jeho recidivy" . . "Non-invasive screening of molecular biomarkers may enable effective surgical intervention through an early diagnosis of the disease. To adopt to the most appropriate diagnostic and therapeutic strategy we need to know molecular factors of the tumor as well as its clinical and histological features.Among possible biomarkers for early detection microRNAs (miRNAs) or mucins that exhibit CRC specific expression may be applied. This study may shed light on the problem of early CRC diagnosis and detection (or CRC relapse detection), which is essential for successful treatment."@en . "2012-04-01+02:00"^^ . . "MiR137" . "MiR137 and its influence on the production of mucin as a potential tool in early diagnosis of colorectal cancer or colorectal cancer relapse"@en . "http://www.isvav.cz/projectDetail.do?rowId=NT13424"^^ . . . "0"^^ . "2015-12-31+01:00"^^ . "Neinvazivn\u00ED vy\u0161et\u0159en\u00ED molekul\u00E1rn\u00EDch marker\u016F u kolorekt\u00E1ln\u00EDho karcinomu m\u016F\u017Ee umo\u017Enit efektivn\u00ED chirurgick\u00FD z\u00E1krok d\u00EDky v\u010Dasn\u00E9 diagn\u00F3ze onemocn\u011Bn\u00ED \u010Di jeho recidivy. Abychom mohli zaujmout tu nejvhodn\u011Bj\u0161\u00ED diagnostickou a l\u00E9\u010Debnou strategii mus\u00EDme zn\u00E1t molekul\u00E1rn\u00ED charakteristiku n\u00E1doru, stejn\u011B jako jeho klinick\u00E9 a histologick\u00E9 chov\u00E1n\u00ED. Proto je zde nal\u00E9hav\u00E1 pot\u0159eba hledat nov\u00E9 neinvazivn\u00ED biomarkery, kter\u00E9 by pomohly k v\u010Dasn\u00E9mu odhalen\u00ED KRC nebo jeho recidivy. Mezi mo\u017En\u00E9 biomarkery pro v\u010Dasnou detekci KRC by se mohla p\u0159i\u0159adit microRNA (miRNA) nebo muciny. Pl\u00E1novan\u00E1 studie m\u016F\u017Ee vn\u00E9st sv\u011Btlo do probl\u00E9mu \u010Dasn\u00E9 detekce a diagn\u00F3zy KRC (nebo detekce KRC relapsu), kter\u00E9 jsou nezbytn\u00E9 pro \u00FAsp\u011B\u0161nou l\u00E9\u010Dbu." . " mucins" . "1"^^ . . . "2015-01-22+01:00"^^ . "1"^^ . . "1"^^ . . "1"^^ . . "MiR137; mucins; early diagnosis of colorectal"@en . . . . "NT13424" . "2014-03-21+01:00"^^ .