. . "0"^^ . . "Program ITAREPS 2.0 vyu\u017E\u00EDv\u00E1 telekomunika\u010Dn\u00EDch a informa\u010Dn\u00EDch technologi\u00ED umo\u017E\u0148uj\u00EDc\u00EDch na automatizovan\u00E9 b\u00E1zi pr\u016Fb\u011B\u017En\u011B detekovat v\u00FDkyvy ve zdravotn\u00EDm stavu nemocn\u00E9ho a zjistit tak s dostate\u010Dn\u00FDm p\u0159edstihem po\u010D\u00E1tky prodrom\u016F hroz\u00EDc\u00EDho relapsu. Tento p\u0159\u00EDstup otev\u00EDr\u00E1 cestu \u010Dasn\u00E9 farmakologick\u00E9 intervenci. \u00DA\u010Dastn\u00EDci (150 pacient\u016F s dg. schizofrenie \u010Di schizoafektivn\u00ED porucha + rodinn\u00ED p\u0159\u00EDslu\u0161n\u00EDci) budou v pom\u011Bru 1:1 randomizov\u00E1ni do interven\u010Dn\u00ED \u010Di kontroln\u00ED skupiny. \u00DA\u010Dastn\u00EDci v aktivn\u00ED skupin\u011B budou t\u00FDdn\u011B po dobu 18 m\u011Bs\u00EDc\u016F zas\u00EDlat syst\u00E9mu v podob\u011B SMS zpr\u00E1vy dotazn\u00EDk \u010Dasn\u00FDch varovn\u00FDch p\u0159\u00EDznak\u016F. V t\u00E9to skupin\u011B obdr\u017E\u00ED p\u0159i l\u00E9ka\u0159 zhor\u0161en\u00ED stavu automaticky generovanou alertn\u00ED e-mailovou zpr\u00E1vu. N\u00E1sledn\u011B bude l\u00E9ka\u0159 reagovat zv\u00FD\u0161en\u00EDm antipsychotick\u00E9 medikace o 20% ze st\u00E1vaj\u00EDc\u00ED d\u00E1vky. V kontroln\u00ED skupin\u011B (s b\u011B\u017Enou l\u00E9\u010Dbou) nebudou \u00FA\u010Dastn\u00EDci do programu ITAREPS 2.0 zahrnuti. Zn\u00E1mky hroz\u00EDc\u00EDho relapsu budou v tomto p\u0159\u00EDpad\u011B zji\u0161\u0165ov\u00E1ny zp\u016Fsobem b\u011B\u017En\u00FDm v ambulantn\u00ED klinick\u00E9 praxi." . "1"^^ . "0"^^ . "0"^^ . "schizophrenia" . . . "The ITAREPS 2.0 program employs telecommunication and information technologies in order to detect fluctuations in longitudinal mental health status of patient with schizophrenia and thus signalize the very early stages of prodromes preceding relapse. This approach opens an avenue towards early pharmacological intervention. Subjects (150 patient with diagnosis of schizophrenia and schizoaffective disorder and their family members) will be randomized at a 1:1 ratio into the active or control group. Participants from the active group will be completing two separate versions of the 10-item Early Warning Signs Questionnaire (EWSQ) upon a weekly SMS request generated automatically by the system during 18 months study duration. In this group, automatically generated e-mail alert message feedback to the investigator will be activated in case of prodrome detection, prompting investigator to antipsychotic dose increase by 20%. The control (treatment-as-usual) group will not use ITAREPS system."@en . . . . " relapse prevention" . . "2013-03-26+01:00"^^ . . . "NT13292" . "schizophrenia; relapse prevention; information technology"@en . . . . "2015-01-22+01:00"^^ . "http://www.isvav.cz/projectDetail.do?rowId=NT13292"^^ . "2012-04-01+02:00"^^ . "ITAREPS 2.0 study: Prospective, randomized, open, controlled study with information and telecommunication technology-aided relapse prevention program in schizophrenia."@en . . . "0"^^ . "2014-12-31+01:00"^^ . . "ITAREPS 2.0: Prospektivn\u00ED, randomizovan\u00E1, otev\u0159en\u00E1, kontrolovan\u00E1 studie s programem prevence relapsu schizofrenie, podporovan\u00FDm informa\u010Dn\u00EDmi a mobiln\u00EDmi technologiemi." .