"http://www.isvav.cz/projectDetail.do?rowId=NT11536"^^ . . "2015-01-22+01:00"^^ . "functional magnetic resonance; diffusion tensor imaging; temporal epilepsy; language reorganization; naming deficit; anteromedial temporal resectio"@en . . "2010-09-01+02:00"^^ . "Funk\u010Dn\u00ED magnetick\u00E1 rezonance a traktografie; vyu\u017Eit\u00ED pro hodnocen\u00ED \u0159e\u010Dov\u00FDch oblast\u00ED u pacient\u016F s tempor\u00E1ln\u00ED epilepsi\u00ED" . "2013-03-26+01:00"^^ . " language reorganization" . . "Tempor\u00E1ln\u00ED resekce je nej\u010Dast\u011Bj\u0161\u00EDm epileptochirurgick\u00FDm z\u00E1krokem. Modern\u00ED funk\u010Dn\u00ED neurozobrazen\u00ED m\u016F\u017Ee hr\u00E1t d\u016Fle\u017Eitou roli v predikci rizika zhor\u0161en\u00ED kognitivn\u00EDch funkc\u00ED, zejm\u00E9na pojmenov\u00E1n\u00ED, po tempor\u00E1ln\u00ED resekci v \u0159e\u010Dov\u011B dominantn\u00ED mozkov\u00E9 hemisf\u00E9\u0159e. C\u00EDlem projektu je stanovit roli funk\u010Dn\u00ED magnetick\u00E9 rezonance (fMR) a kombinovan\u00E9 fMR/traktografie v ur\u010Den\u00ED organizace \u0159e\u010Dov\u00FDch funkc\u00ED a schopnosti pojmenov\u00E1n\u00ED u pacient\u016F s tempor\u00E1ln\u00ED epilepsi\u00ED. Data z funk\u010Dn\u00EDho neurozobrazen\u00ED budou korelov\u00E1na s v\u00FDsledky neuropsychologick\u00FDch test\u016F rutinn\u00EDch a experiment\u00E1ln\u00EDch (pojmenov\u00E1n\u00ED), s klinick\u00FDmi daty a s v\u00FDsledky MR volumetrie tempor\u00E1ln\u00EDho p\u00F3lu a hippokampu. Do studie budou za\u0159azeni pacienti s refraktern\u00ED epilepsi\u00ED tempor\u00E1ln\u00ED laloku, indikovan\u00ED k opera\u010Dn\u00EDmu v\u00FDkonu. Studie zahrne cca 60 pacient\u016F a 20 kontroln\u00EDch subjekt\u016F. Projekt poskytne krom\u011B d\u016Fle\u017Eit\u00FDch informac\u00ED stran organizace \u0159e\u010Dov\u00FDch oblast\u00ED u pacient\u016F s tempor\u00E1ln\u00ED epilepsi\u00ED zejm\u00E9na mo\u017Enost predikce rizika poopera\u010Dn\u00EDho deficitu v pojmenov\u00E1n\u00ED." . . "NT11536" . "0"^^ . . "2"^^ . "2014-12-31+01:00"^^ . . "2"^^ . "1"^^ . . "Language reorganisation and naming deficit in temporal lobe epilepsy patients; assessment by functional magnetic resonance imaging and tractography"@en . "Temporal lobe resection is the most common type of epilepsy surgery. Modern functional neuroimaging may play an important role in prediction of cognitive functions decline, in particular naming abilities, following speech dominant temporal lobe resection. The aim of the project is to assess the role of functional MR (fMR) and fMR seeded tractography in diagnostics of language function and organisation in temporal lobe epilepsy (TLE) patients. The neuroimaging functional data will be correlated to results of neuropsychological testing, both routine and experimental (naming), and to clinical characteristics and MRI volumetric measurements of temporal pole and hippocampus. Patients with refractory TLE indicated for epilepsy surgery will be included in the study. The study will include up to 60 patients and 20 controls. The results will provide important information on language areas organisation in TLE patients and also may have potential to predict extent of naming deficit following surgery."@en . . "1"^^ . . . . "functional magnetic resonance" . " naming deficit" . . " temporal epilepsy" . . . . " diffusion tensor imaging" . . . .