. "Metoda frakcionovan\u00E9 plasmatick\u00E9 separace a adsorpce v experimentu vede k efektivn\u00EDmu sn\u00ED\u017Een\u00ED intrakrani\u00E1ln\u00EDho tlaku u akutn\u00EDho selh\u00E1n\u00ED jater"@cs . . . . "Fractionated plasma separation and adsorption is effective in intracranial pressure control during acute liver failure in experiment"@en . . "2014-09-02+02:00"^^ . "1"^^ . . . "Acute liver failure - resectio"@en . "0"^^ . "2"^^ . "2013-03-26+01:00"^^ . . "2"^^ . . . "http://www.isvav.cz/projectDetail.do?rowId=NT11463"^^ . "2010-09-01+02:00"^^ . "The outcomes as decrease of extracellular brain ammoniac, lactate and energetic needs changes after using FPSA in ALF treatment has never been published before. Team of authors is aiming to proof the benefit of FPSA in ALF treatment, decrease of energetic needs of the brain in large experimental model, minipig one respectively. On top of that authors want to test hemodynamics and systemic inflammatory changes. Above mentioned benefits from FPSA might positively affect ASF treatment outcomes. Project results will be used to design guidelines for ALF treatment to be used in human medicine."@en . . . "NT11463" . "Doposud nebyl experiment\u00E1ln\u011B prok\u00E1z\u00E1n vliv FPSA na hladinu patogenn\u00EDch metabolit\u016F (amoniak, glutamin, glutam\u00E1t) v cerebr\u00E1ln\u00EDm intersticiu a na energetick\u00FD metabolismus mozku v pr\u016Fb\u011Bhu ASJ. \u0158e\u0161itelsk\u00FD t\u00FDm projektu si klade za c\u00EDl prok\u00E1zat, \u017Ee FPSA v l\u00E9\u010Db\u011B experiment\u00E1ln\u00EDho chirurgick\u00E9ho resek\u010Dn\u00EDho modelu ASJ u velk\u00E9ho laboratorn\u00EDho zv\u00ED\u0159ete (prase) pozitivn\u011B ovliv\u0148uje patologick\u00E9 d\u011Bje vedouc\u00ED k rozvoji mozkov\u00E9ho otoku u ASJ a t\u00EDm p\u0159\u00EDzniv\u011B ovliv\u0148uje jeho pr\u016Fb\u011Bh. D\u00E1le cht\u011Bj\u00ED auto\u0159i zhodnotit, jak FPSA ovliv\u0148uje hemodynamiku a syst\u00E9movou z\u00E1n\u011Btlivou odpov\u011B\u010F organizmu v pr\u016Fb\u011Bhu AJS. V\u00FDsledky studie p\u0159isp\u011Bj\u00ED k vytvo\u0159en\u00ED doporu\u010Den\u00E9ho diagnostick\u00E9ho a terapeutick\u00E9ho postupu aplikovateln\u00E9ho v klinick\u00E9 praxi." . "2013-12-31+01:00"^^ . "Ovlivn\u011Bn\u00ED intrakrani\u00E1ln\u00EDch parametr\u016F v pr\u016Fb\u011Bhu nebiologick\u00E9 elimina\u010Dn\u00ED l\u00E9\u010Dby akutn\u00EDho selh\u00E1n\u00ED jater v experimentu" . "Intracranial parameter changes during acute liver failue treated by non-biological elimination in minipig experimental model"@en . . . . . "0"^^ . . .