"1"^^ . . . "0"^^ . . "P\u0159edkl\u00E1dan\u00FD projekt je zam\u011B\u0159en na ur\u010Den\u00ED vztahu urologick\u00FDch a endokrinologick\u00FDch faktor\u016F p\u0159i hormon\u00E1ln\u00ED substitu\u010Dn\u00ED terapii u mu\u017E\u016F s Kallmannov\u00FDm syndromem. Zahrnuje urologick\u00E9 a endokrinologick\u00E9 vy\u0161et\u0159en\u00ED, hormon\u00E1ln\u00ED vy\u0161et\u0159en\u00ED, t\u0159\u00EDdimenzion\u00E1ln\u00ED transrekt\u00E1ln\u00ED sonografii prostaty a varlat, antropometrick\u00E9 vy\u0161et\u0159en\u00ED zevn\u00EDch pohlavn\u00EDch org\u00E1n\u016F a vyhodnocen\u00ED mik\u010Dn\u00EDch a sexu\u00E1ln\u00EDch funkc\u00ED. P\u0159edpokl\u00E1d\u00E1me vyu\u017Eit\u00ED z\u00EDskan\u00FDch informac\u00ED pro zp\u0159esn\u011Bn\u00ED \u00FAsp\u011B\u0161nosti a rizik hormon\u00E1ln\u00ED substitu\u010Dn\u00ED terrapie u mu\u017E\u016F s Kallmannov\u00FDm syndromem. Projekt p\u0159edstavuje nejkomplexn\u011Bj\u0161\u00ED a nejrozs\u00E1hlej\u0161\u00ED studii vztahu urologick\u00FDch a endokrinologick\u00FDch faktor\u016F a hormon\u00E1ln\u00ED substitu\u010Dn\u00ED terapie u mu\u017E\u016F s Kallmannov\u00FDm syndromem." . " testis" . . "2011-12-31+01:00"^^ . " antropometry" . "Urologick\u00E9 a endokrinologick\u00E9 faktory hormon\u00E1ln\u00ED substitu\u010Dn\u00ED terapie u pacient\u016F s Kallmannov\u00FDm syndromem" . "2009-01-01+01:00"^^ . "Kallmann syndrome" . . . " prostate" . . . "2011-08-08+02:00"^^ . . . " androgens" . . "Kallmann syndrome; androgens; transrectal ultrasonography; prostate; testis; hormones; antropometry; sexual function"@en . "Byly z\u00EDsk\u00E1ny objektivn\u00ED \u00FAdaje o rizic\u00EDch a benefitech dlouhodob\u00E9 substitu\u010Dn\u00ED l\u00E9\u010Dby testosteronem u nemocn\u00FDch s Kallmannov\u00FDm syndromem a i u jin\u00FDch mu\u017Esk\u00FDch hypogonadism\u016F, konkr\u00E9tn\u011B nakolik HST ovlivn\u00ED riziko benign\u00ED hyperpl\u00E1zie a karcinomu prostaty ."@cs . "http://www.isvav.cz/projectDetail.do?rowId=NS9983"^^ . "The project is focused on the determination of the relationship of the urological and endocrinological factors of hormonal substitution therapy in patients with Kallmann syndrome. Project includes urological and endocrinological examination, hormonal analysis, 3D transrectal ultrasonography of prostate and testes, antropometrical examination external genitals and determination of miction and sexual function. We assume to utilize the results for optimize the therapeutically-diagnostic approach and specification of risk hormonal substitution therapy in patients with Kallmann syndrome. The project presents the most complex and the most extensive study in relation of urological and endocrinological factors of hormonal substitution therapy in patients with Kallmann syndrome."@en . "Risks and benefits of long-term substitution therapy of patients with Kallmann syndrome and of other hypogonadal men with testosterone were evaluated, with regard to development of benign hyperplasia and carcinoma of the prostate"@en . . . . . "2013-10-31+01:00"^^ . . . "NS9983" . . " transrectal ultrasonography" . . "1"^^ . "Urological and endocrinological factors of hormonal substitution therapy in patients with Kallmann syndrome"@en . . "1"^^ . " hormones" . "1"^^ .