. "0"^^ . " Predictive factors" . . "2010-12-31+01:00"^^ . "Study of selected predictive factors for adjuvant chemotherapy in patients with operable lung cancer with the aim of suitable patient selection for curative chemotherapeutic intervention. A combination of immunohistochemical and molecular biology marker analyses on a retrospective sample of patients with evaluated survival after adjuvant chemotherapy in the course of prognostic interpretation. Comparison of results with prospective study. Comparison of detected chemosensitivity by MTT test with pathological markers. Recommendation for additional standardised procedures for evaluating predictive treatment factors before beginning chemotherapy in patients with resected tumours."@en . "2009-01-01+01:00"^^ . . "The results of the project bring about new information about the composition of adjuvant chemotherapy for the various stages of NSCL and in addition they enable better prediction of NSCLC patients prognosis."@en . "2010-11-04+01:00"^^ . . . "Non-small lung cancers" . . . " Activate mutation" . "NS9959" . . "2012-01-10+01:00"^^ . . "V\u00FDsledky \u0159e\u0161en\u00E9ho projektu p\u0159in\u00E1\u0161ej\u00ED nov\u00E9 informace pro rozhodov\u00E1n\u00ED o slo\u017Een\u00ED adjuvantn\u00ED chemoterapie NSCLC a d\u00E1le umo\u017E\u0148uj\u00ED lep\u0161\u00ED vyj\u00E1d\u0159en\u00ED k progn\u00F3ze onemocn\u011Bn\u00ED."@cs . . . "Predictive factors for adjuvant chemotherapy in patients with operable stage of non-small cell lung cancer"@en . "Studium vytipovan\u00FDch prediktivn\u00EDch faktor\u016F adjuvantn\u00ED chemoterapie u pacient\u016F s operabiln\u00EDm plicn\u00EDm karcinomem s c\u00EDlem selekce vhodn\u00FDch pacient\u016F ke kurabiln\u00EDmu chemoterapeutick\u00E9mu z\u00E1sahu. Kombinace imunohistochemick\u00FDch a molekul\u00E1rn\u011B biologick\u00FDch anal\u00FDz marker\u016F u retrospektivn\u00EDho souboru pacient\u016F s vyhodnocen\u00EDm p\u0159e\u017E\u00EDv\u00E1n\u00ED po adjuvantn\u00ED chemoterapii p\u0159i interpretaci prognostick\u00E9ho v\u00FDznamu. Srovn\u00E1n\u00ED zji\u0161t\u011Bn\u00E9 chemorezistence z in vitro kultivovan\u00FDch n\u00E1dorov\u00FDch bun\u011Bk p\u0159i MTT testu s v\u00FDsledky detekovan\u00FDch patologi\u00ED sledovan\u00FDch molekul\u00E1rn\u00EDch marker\u016F. Porovn\u00E1n\u00ED v\u00FDsledk\u016F s prospektivn\u00ED studi\u00ED. Navr\u017Een\u00ED doporu\u010Den\u00ED pro dopln\u011Bn\u00ED standardn\u00EDho postupu o vy\u0161et\u0159en\u00ED prediktivn\u00EDch faktor\u016F p\u0159ed zah\u00E1jen\u00EDm vlastn\u00ED terapie po resekci n\u00E1doru dle dosa\u017Een\u00FDch v\u00FDsledk\u016F." . "14"^^ . . . "14"^^ . "Non-small lung cancers; Adjuvant chemotherapy; Predictive factors; Multidrug resistance; Expression of markers; Activate mutation; MTT test"@en . " Multidrug resistance" . . . " Adjuvant chemotherapy" . . "1"^^ . . . . "1"^^ . "http://www.isvav.cz/projectDetail.do?rowId=NS9959"^^ . " Expression of markers" . "Prediktivn\u00ED faktory aplikace adjuvantn\u00ED chemoterapie u pacient\u016F s operabiln\u00EDm st\u00E1diem nemalobun\u011B\u010Dn\u00E9ho karcinomu plic" .