. "The aim of experimantal study is to verify a possibility of use of MSCs in treatment of growth plate lesion by its graft in scafold on the base of interpenetrating polymerizing net in surrounding with cultivated allogenic chondrocytes. Expected effect is histologically verified growth plate reparation, inhibition of angular deformity inception and elimination of bone length growth limitation."@en . . " MSCs" . "http://www.isvav.cz/projectDetail.do?rowId=NS9896"^^ . . "2012-01-10+01:00"^^ . "2010-12-31+01:00"^^ . . . "Nanotechnology and tissue engineering used in growth plate arrest therapy - experimental study"@en . "2010-07-16+02:00"^^ . . "0"^^ . . "1"^^ . "2009-01-01+01:00"^^ . "The project proved that the implantation of the proposed composite scaffold gives good outcomes in prevention of growth disturbance of the distal femoral epiphysis in animal model."@en . . "2"^^ . "Vyu\u017Eit\u00ED nanotechnologi\u00ED a biomateri\u00E1l\u016F v kombinaci s mezenchymov\u00FDmi kmenov\u00FDmi bu\u0148kami v l\u00E9\u010Db\u011B po\u0161kozen\u00E9 fyz\u00E1rn\u00ED r\u016Fstov\u00E9 plot\u00E9nky - experiment\u00E1ln\u00ED studie." . "1. C\u00EDlem experiment\u00E1ln\u00ED studie je ov\u011B\u0159it mo\u017Enost vyu\u017Eit\u00ED MSCs v l\u00E9\u010Db\u011B poran\u011Bn\u00ED r\u016Fstov\u00E9 plot\u00E9nky jejich transplantac\u00ED ve skafoldu na b\u00E1zi interpenetruj\u00EDc\u00ED polymerizuj\u00EDc\u00ED s\u00EDt\u011B v prost\u0159ed\u00ED s kultivovan\u00FDmi allogenn\u00EDmi chondrocyty. 2. O\u010Dek\u00E1van\u00FDm efektem je reparace r\u016Fstov\u00E9 plot\u00E9nky ov\u011B\u0159en\u00E1 histologicky, zabr\u00E1n\u011Bn\u00ED vzniku angula\u010Dn\u00EDch deformit a eliminace omezen\u00ED r\u016Fstu kosti do d\u00E9lky." . . . . . . "9"^^ . . "9"^^ . . . "NS9896" . "bone bridge" . . . "bone bridge; MSCs; transplantation (graft)"@en . "Pr\u00E1ce prok\u00E1zala, \u017Ee implantace navr\u017Een\u00E9ho kompozitn\u00EDho nosi\u010De vykazuje dobr\u00E9 v\u00FDsledky v prevenci r\u016Fstov\u00FDch poruch dist\u00E1ln\u00ED femor\u00E1ln\u00ED epif\u00FDzy v modelu na zv\u00ED\u0159eti."@cs . .