. "http://www.isvav.cz/projectDetail.do?rowId=NS9738"^^ . . "Vytvo\u0159ena nov\u00E1 l\u00E9\u010Debn\u00E1 metoda (hemorheofereza),kter\u00E1 zlep\u0161uje stav s\u00EDtnice p\u0159i onemocn\u011Bn\u00ED suchou formou makul\u00E1rn\u00ED degenerace a br\u00E1n\u00ED vzniku vlhk\u00E9 formy degenerace."@cs . . "2011-12-31+01:00"^^ . . "2011-08-08+02:00"^^ . "10"^^ . "10"^^ . . . "Influence of rheopheresis therapy on retinal function in age-related macular degeneration"@en . "2013-10-31+01:00"^^ . . " rheopheresis" . "Established new curative method (haemorheopheresis) which improves state of diseased retina at the dry form of macular degeneration and prevents the development of the wet form of degeneration."@en . " plasma filtration" . . . . . "2009-01-01+01:00"^^ . " soft druses" . . "NS9738" . . . "Age-related macular degeneration (AMD) is the main cause of blindness in people over 50 years of age in industrialized countries. Rheopheresis therapy may prevent transition of the dry to devastating wet form of AMD and even improve function of the retina. Rheopheresis markedly lowers certain precisely defined spectrum of high-molecular agents: LDL cholesterol, fibrinogen, immunoglobulins, alpha2-macroglobulin, von Willebrand factor, viscosity of plasma and whole blood, all pathologically relevant factors in AMD. Based on functional retinal changes, evaluated by electroretinography and by precisely defined immunologically and rheologically important factors, indication criteria, therapy duration and procedure intensity would be designed as well as optimal follow-up scheme."@en . . . . " electroretinography (ERG)" . "0"^^ . "Vliv syst\u00E9mov\u00E9 l\u00E9\u010Dby rheofer\u00E9zou na funk\u010Dn\u00ED stav s\u00EDtnice u v\u011Bkem podm\u00EDn\u011Bn\u00E9 makul\u00E1rn\u00ED degenerace" . "V\u011Bkem podm\u00EDn\u011Bn\u00E1 makul\u00E1rn\u00ED degenerace (AMD) je hlavn\u00ED p\u0159\u00ED\u010Dinou slepoty obyvatel rozvinut\u00FDch zem\u00ED star\u0161\u00EDch 50 let. L\u00E9\u010Dba rheofer\u00E9zou m\u016F\u017Ee zabr\u00E1nit p\u0159echodu such\u00E9 formy do devastuj\u00EDc\u00ED vlhk\u00E9 formy, funk\u010Dn\u00ED stav s\u00EDtnice m\u016F\u017Ee b\u00FDt terapi\u00ED dokonce zlep\u0161en. Rheofer\u00E9za v\u00FDrazn\u011B sni\u017Euje p\u0159esn\u011B definovan\u00E9 spektrum vysokomolekul\u00E1rn\u00EDch l\u00E1tek: LDL cholesterolu, fibrinogenu, imunoglobulin\u016F, alpha2makroglobulinu, von Willebrandova faktoru a viskozitu plazmy i cel\u00E9 krve, co\u017E jsou patologicky relevantn\u00ED faktory u AMD. Na z\u00E1klad\u011B funk\u010Dn\u00EDch zm\u011Bn s\u00EDtnice v \u010Dase hodnocen\u00FDch elektroretinograficky a up\u0159esn\u011Bn\u00EDm v\u00FDznamu imunologicky a rheologicky v\u00FDznamn\u00FDch faktor\u016F, budou zp\u0159esn\u011Bna indika\u010Dn\u00ED krit\u00E9ria, d\u00E9lka l\u00E9\u010Dby a intenzita procedur a stanoveno optim\u00E1ln\u00ED sledovac\u00ED sch\u00E9ma." . . "AMD; soft druses; rheopheresis; plasma filtration; electroretinography (ERG); multifocal ERG; pattern ERG"@en . "AMD" . . "1"^^ . "1"^^ . " multifocal ERG" .