"NS9661" . . " oxidative stress" . "1"^^ . "1"^^ . "To improve knowledge about pathological homocysteine metabolism and relation to oxidative stress, gonadal function and DNA structure of human germinal cells. To analyze predictive value of homocysteine, oxidative stress and sperm chromatine integrity for examination and treatment of human infertility. To identify health risks factors of life style and their impact on reproductive health and improve effective prevention."@en . "Z\u00EDsk\u00E1n\u00ED nov\u00FDch poznatk\u016F o patologick\u00E9m metabolismu homocysteinu, jeho souvislosti s oxida\u010Dn\u00EDm stresem a po\u0161kozen\u00EDm DNA lidsk\u00FDch z\u00E1rode\u010Dn\u00FDch bun\u011Bk a funkc\u00ED gon\u00E1d. Ov\u011B\u0159en\u00ED prediktivn\u00ED hodnoty vy\u0161et\u0159en\u00ED homocysteinu, oxida\u010Dn\u00EDho stresu a integrity chromatinu spermie pro diagnostiku a l\u00E9\u010Dbu poruch plodnosti. Identifikace zdravotn\u00EDch rizik vypl\u00FDvaj\u00EDc\u00EDch ze zp\u016Fsobu \u017Eivota a jejich vlivu na reproduk\u010Dn\u00ED zdrav\u00ED, zlep\u0161en\u00ED p\u0159edpoklad\u016F pro efektivn\u00ED prevenci." . . "infertility; homocysteine; sperm; follicular fluid; assisted reproduction; oxidative stress; chromatine integrity"@en . . " assisted reproduction" . "infertility" . "16"^^ . "2011-08-08+02:00"^^ . "2011-12-31+01:00"^^ . "Impact of homocysteine metabolism on human infertility"@en . "16"^^ . "2009-01-01+01:00"^^ . . "http://www.isvav.cz/projectDetail.do?rowId=NS9661"^^ . . " homocysteine" . "Vliv metabolismu homocysteinu na poruchy plodnosti." . . . " sperm" . . . . . "2013-10-31+01:00"^^ . " follicular fluid" . . . "Vypracov\u00E1ny a do klinick\u00E9 praxe zavedeny nov\u00E9 metody vy\u0161et\u0159en\u00ED homocysteinu, thiol\u016F a fragmentace chromatinu spermi\u00ED p\u0159i lidsk\u00E9 reprodukc\u00ED a oxida\u010Dn\u00EDm stresu; po\u0161kozen\u00ED spermi\u00ED zobrazeno mikroskopem atom\u00E1rn\u00EDch sil a digit\u00E1ln\u00EDm holografick\u00FDm mikroskopem."@cs . "New laboratory assays of homocysteine, thiols and sperm chromatin fragmentation in human reproduction and oxidative stress were introduced in clinical practice; sperm patology was assessed by atomic force and digital holographic microscopies."@en . . . . . . "0"^^ .