"Long term outcome in children with CDH with respect of surgical technique was a goal of the study. New criteria for Gore-Tex patch reconstruction optimizes surgical technique. Lung function tests in infants are valid for evaluation of lung development."@en . . "2011-08-08+02:00"^^ . . . . "Presented project is focused on long-term effect of diaphragmatic reconstruction with synthetic nonabsorbable patch on development of lung function and formation of skeletal deformity in children with congenital diaphragmatic hernia. Both in retrospective and prospective study the data of newborns with patch reconstruction of diaphragm will be compared with data of newborns after primary repair of diaphragm. Results of both study groups will be statistically analyzed and compared with population standard. The study group of the retrospective part will include 144 children who underwent diaphragmatic reconstruction in 1996-2007. Evaluation of skeletal deformity and lung function test will be performed. In prospective part in 2009-2011 the perinatal categorization of the severity of disease in c. 50 newborns per study period will be performed. Lung function test will be performed by new methods of baby-bodyplethysmography in noncooperating children less than one year of life."@en . " lung function" . "congenital diaphragmatic herni; skeletal abnormalities; lung function; diaphragmatic reconstruction; Gore-Tex"@en . "2009-01-01+01:00"^^ . " skeletal abnormalities" . . . "congenital diaphragmatic herni" . "Vliv chirurgick\u00E9ho postupu na v\u00FDvoj plicn\u00EDch funkc\u00ED a skelet\u00E1ln\u00EDch deformit u d\u011Bt\u00ED s vrozenou br\u00E1ni\u010Dn\u00ED k\u00FDlou" . . "http://www.isvav.cz/projectDetail.do?rowId=NS10572"^^ . "NS10572" . "Projekt \u0159e\u0161il vliv operace na v\u00FDvoj d\u011Bt\u00ED s vrozenou br\u00E1ni\u010Dn\u00ED k\u00FDlou. Nov\u00E1 metodika kriteri\u00ED pro rekonstrukci br\u00E1nice Gore-Texovou z\u00E1platou optimalizuje chirurgick\u00FD postup. M\u011B\u0159en\u00EDm plicn\u00EDch funkc\u00ED u nespolupracuj\u00EDc\u00EDch d\u011Bt\u00ED lze posoudit v\u00FDvoj plic."@cs . . "2011-12-31+01:00"^^ . . . "0"^^ . . "Effect of surgical management on development of lung function and formation of skeletal deformity in children with congenital diaphragmatic hernia."@en . . "2013-10-31+01:00"^^ . "1"^^ . . . . "4"^^ . "0"^^ . "4"^^ . "Projekt je zam\u011B\u0159en na vyhodnocen\u00ED dlouhodob\u00E9ho vlivu rekonstrukce br\u00E1nice syntetickou z\u00E1platou na v\u00FDvoj plicn\u00EDch funkc\u00ED a skelet\u00E1ln\u00EDch deformit u d\u011Bt\u00ED s vrozenou br\u00E1ni\u010Dn\u00ED k\u00FDlou. V retrospektivn\u00ED i prospektivn\u00ED \u010D\u00E1sti projektu bude porovn\u00E1na skupina d\u011Bt\u00ED s rekonstrukc\u00ED br\u00E1nice syntetickou z\u00E1platou a kontroln\u00ED skupina operovan\u00E1 prostou plastikou br\u00E1nice. V\u00FDsledky obou skupin budou statisticky vyhodnoceny a vzta\u017Eeny k popula\u010Dn\u00EDm norm\u00E1m plicn\u00EDch funkc\u00ED a antropometrick\u00FDm norm\u00E1m. Data retrospektivn\u00ED \u010D\u00E1sti budou z\u00EDsk\u00E1na ze souboru 144 d\u011Bt\u00ED l\u00E9\u010Den\u00FDch v rozmez\u00ED 1996 - 2007. U t\u011Bchto d\u011Bt\u00ED bude provedeno vy\u0161et\u0159en\u00ED skelet\u00E1ln\u00EDch deformit a funk\u010Dn\u00ED vy\u0161et\u0159en\u00ED plic. V prospektivn\u00ED \u010D\u00E1sti 2009-2011 bude u cca 50 novorozenc\u016F provedena perinat\u00E1ln\u00ED kategorizace z\u00E1va\u017Enosti onemocn\u011Bn\u00ED. Pr\u016Fb\u011B\u017En\u011B bude sledov\u00E1n v\u00FDvoj plicn\u00EDch funkc\u00ED a skelet\u00E1ln\u00EDch deformit v z\u00E1vislosti na velikosti defektu a pou\u017Eit\u00E9 opera\u010Dn\u00ED technice. Plicn\u00ED funkce budou p\u0159i vyu\u017Eit\u00ED nov\u00E9 metodiky pletyzmografie vy\u0161et\u0159ov\u00E1ny ji\u017E v prvn\u00EDm roce \u017Eivota." . . " diaphragmatic reconstruction" . . .