. "Byla vytvo\u0159ena a publikov\u00E1na validovan\u00E1 metodika pro stanoven\u00ED a detekci toxin\u016F muchom\u016Frky zelen\u00E9, \u010Derven\u00E9 a tygrovan\u00E9 v biologick\u00E9m materi\u00E1lu pomoc\u00ED HPLC-DAD a LC-MS, vyu\u017Eiteln\u00E1 v \u010Desk\u00FDch i zahrani\u010Dn\u00EDch toxikologick\u00FDch a obdobn\u00FDch laborato\u0159\u00EDch."@cs . "0"^^ . "Postatou projektu je v\u00FDvoj analytick\u00FDch metod umo\u017E\u0148uj\u00EDc\u00EDch pr\u016Fkaz a stanoven\u00ED obsahov\u00FDch, biologicky \u00FA\u010Dinn\u00FDch l\u00E1tek muchom\u016Frky zelen\u00E9, tygrovan\u00E9 a \u010Derven\u00E9 v\u00A0krvi, mo\u010Di, pop\u0159. \u017Ealude\u010Dn\u00EDm obsahu intoxikovan\u00FDch pacient\u016F. Ned\u00EDlnou sou\u010D\u00E1st\u00ED je vypracov\u00E1n\u00ED extrak\u010Dn\u00ED metody pro izolaci toxin\u016F muchom\u016Frek z biologick\u00E9ho materi\u00E1lu s n\u00E1slednou identifikac\u00ED a kvantifikac\u00ED t\u011Bchto l\u00E1tek chromatografick\u00FDmi metodami LC-MS a HPLC-DAD." . "3"^^ . "The aim of the project is to develop suitable analytical methods for identification and determination of the toxins of the Amanita phalloides, Amanita pantherina and Amanita muscaria in blood, urine and gastric content of intoxicated patients. To fulfil the aim, appropriate extraction method for isolation of relevant toxins from biological matrices together with sensitive and specific chromatographic methods (HPLC-DAD, LC-MS) will be elaborated."@en . . "0"^^ . . "3"^^ . "1"^^ . "2013-10-31+01:00"^^ . "2011-08-08+02:00"^^ . . . . . . "2009-01-01+01:00"^^ . . . "The Objective Analytical Method for Amanita Intoxication Diagnosis"@en . . . " muscimol" . " amanitin" . "mushroom poisoning; muscimol; ibotenic acid; muscarine; amanitin; phalloidin; LC-MS; HPLC-DAD; determination"@en . " HPLC-DAD" . . "Objektivn\u00ED analytick\u00E1 metoda k diagnostice intoxikac\u00ED muchom\u016Frkami" . "mushroom poisoning" . . "Validate methodics for identification and assessment of toxine of Amanita phalloides, A. pantherina and A. muscaria in biological material by means of HPLC-DAD a LC-MS was created and publicated.Methods can be use in Czech and abroad tox. laboratories."@en . "2011-12-31+01:00"^^ . " muscarine" . . " LC-MS" . . "http://www.isvav.cz/projectDetail.do?rowId=NS10269"^^ . "NS10269" . " ibotenic acid" . . . " phalloidin" .