. "2012-01-10+01:00"^^ . . "U 50 pts s FSGS a IgA nefropath. bylo vyhodnoceno 90 gen\u016F exprimovan\u00FDch v ledvin\u00E1ch a prok\u00E1z\u00E1no, \u017Ee FSGS a dal\u0161\u00ED skupiny se li\u0161\u00ED v profilech imunitn\u00ED gen. exprese. Anal\u00FDza C/A polymorf. VEGF prok\u00E1zala zv\u00FD\u0161enou prev. CC genotyp u FSGS"@cs . "2007-01-01+01:00"^^ . . . "http://www.isvav.cz/projectDetail.do?rowId=NR9523"^^ . "Polymorfismy a intraren\u00E1ln\u00ED exprese proz\u00E1n\u011Btliv\u00FDch gen\u016F u Fok\u00E1ln\u011B segment\u00E1ln\u00ED glomeruloskler\u00F3zy a jejich vztah k pr\u016Fb\u011Bhu onemocn\u011Bn\u00ED" . . "1"^^ . "2010-12-31+01:00"^^ . " expression of genes" . "1"^^ . . " fibrosis" . "0"^^ . . . "FSGS" . . . " proteinuria" . "Gene polymorphisms and intrarenal expression of genes in Focal segmental glomerulosclerosis and their relation to progression of the disease"@en . "FSGS; polymorphisms; expression of genes; proteinuria; cytokines; fibrosis; biopsy"@en . . . "Anotace I: Sledovat korelaci mezi intraren\u00E1ln\u00ED expres\u00ED gen\u016F pro MCP-1, RANTES, TGFbeta1, HGF, BMP a VEGF, infiltrac\u00ED ledvinn\u00E9 tk\u00E1n\u011B leukocyty, v\u00FD\u0161\u00ED proteinurie a progrese Fok\u00E1ln\u011B segment\u00E1ln\u00ED glomeruloskler\u00F3zy. Anotace II: Zjistit, zda nositel\u00E9 vlohy pro vysokou produkci proz\u00E1n\u011Btliv\u00FDch cytokin\u016F maj\u00ED vy\u0161\u0161\u00ED riziko vzniku klinicky z\u00E1va\u017En\u00E9 proteinurie a progrese Fok\u00E1ln\u011B segment\u00E1ln\u00ED glomeruloskler\u00F3zy" . " polymorphisms" . "6"^^ . "6"^^ . " cytokines" . . "I: To observe a correlation among an intrarenal expression of genes for MCP-1, RANTES, TGFbeta1, HGF, BMP and VEGF, an infiltration of renal tissue by leukocytes, an ammount of proteinuria and the progression of FSGS. II: To investigate if the carriers of a gene polymorphism causing high production of the inflammation cytokines have higher risk of significant proteinuria and progression of FSGS."@en . . . "In 50 pts with FSGS and IgA nefropathy we analyzed 90 ren. gene expressions and found specif. immune gene profiles in FSGS and other pts group. Analysis of C/A polymorphism of VEGF showed increased prevalence of CC genotype in FSGS"@en . . . "NR9523" . .