"dyslipidaemia; atherosclerosis; genetic polymorphism; statins; prevention; efficacy; treatment"@en . . "http://www.isvav.cz/projectDetail.do?rowId=NR9411"^^ . "2007-01-01+01:00"^^ . . " statins" . "Response to hypolipidemic treatment is genetically regulated. We will study decreases of plasma lipids depending on candidate genes for apo E, A1 and A5, cytochrome P4503A4, hepatic lipase, cholesterol 7alfa hydroxylase and ABC -G8 and -A1 transporters."@en . " genetic polymorphism" . "2009-12-31+01:00"^^ . "Genetic determination of the hypolipidemic treatment efficacy"@en . . . . . "0"^^ . . "Odpov\u011B\u010F na l\u00E9\u010Dbu hypolipidemiky je regulov\u00E1na i geneticky. Budeme sledovat pokles lipidov\u00FDch parametr\u016F v z\u00E1vislosti na genech pro apolipoproteiny E, A1 a A5, pro cytochrom P4503A4, jatern\u00ED lip\u00E1zu, cholesterol 7alfa hydroxyl\u00E1zu a ABC transport\u00E9ry G8 a A1." . . " efficacy" . "1"^^ . "NR9411" . "1"^^ . "dyslipidaemia" . " prevention" . " atherosclerosis" . "2009-12-18+01:00"^^ . . "2011-04-27+02:00"^^ . . . "The results suggest that variants of the apoA5 and apoE polymorphism significantly modulate therapeutic effect of statins."@en . "V\u00FDsledky ukazuj\u00ED, \u017Ee odpov\u011B\u010F na l\u00E9\u010Dbu statiny v\u00FDrazn\u011B moduluj\u00ED varianty v genech pro apoA5 a apoE."@cs . . . "24"^^ . . . "24"^^ . . . . . "Genetick\u00E1 determinace \u00FA\u010Dinnosti hypolipidemick\u00E9 l\u00E9\u010Dby" . .