"2010-06-30+02:00"^^ . " plaque echogenity" . "This study was performed to obtain a new assessment of the coronary artery impairment prediction (e.g. numbers of plaque, plague voluem and plague composition) fron non invasive tests and it has been demonstrated that such approach is possible."@en . "atherosclerosis; intravascular ultrasound; virtual histology; intima media thickness; plaque echogenity; gene polymorphisms; NO and CO; acute coronary syndromes"@en . . "2012-01-10+01:00"^^ . "2007-01-01+01:00"^^ . "Assessment of extent and composition of atherosclerotic plaques in coronary arteries based on ultrasonographic investigation of carotid arteries and polymorphisms of specific genes"@en . " NO and CO" . "NR9214" . . "http://www.isvav.cz/projectDetail.do?rowId=NR9214"^^ . "6"^^ . . "6"^^ . . "I. Hodnocen\u00ED vztahu mezi posti\u017Een\u00EDm karotick\u00FDch tepen v kombinaci s vy\u0161et\u0159en\u00EDm genetick\u00FDch polymorfism\u016F gen\u016F pro proteiny produkuj\u00EDc\u00ED plynn\u00E9 sign\u00E1ln\u00ED molekuly NO a CO a posti\u017Een\u00EDm koron\u00E1rn\u00EDch tepen. II. Genetick\u00E9 polymorfismy budou studov\u00E1ny u endotelov\u00E9 a inducibiln\u00ED synt\u00E1zy oxidu dusnat\u00E9ho (produkce NO) a hem oxygen\u00E1zy-1 (produkce CO). III. C\u00EDlem studie je stanoven\u00ED mo\u017Enosti predikce koron\u00E1rn\u00EDho posti\u017Een\u00ED podle neinvazivn\u011B vy\u0161et\u0159en\u00E9ho posti\u017Een\u00ED karotid a polymorfizm\u016F ve v\u00FD\u0161e uveden\u00FDch genech." . "I. The proposed project assesses the relationship between ultrasonographic findings in carotid arteries in combination with investigation of genetic polymorphisms of genes involved in gas molecules production. II. Genetic polymorphisms will be studied in endothelial and inducible s nitric oxide synthases (production of NO) and heme oxygenase-1 (production of CO). III. Aim of the study is evaluation of possibilities to predict extent and risk features of atherosclerotic plaques inside coronary arteries based on non-invasive ultrasonic examination of carotid arteries together with analysis of polymorhisms in genes mentioned above."@en . . "Byla studov\u00E1na mo\u017Enost p\u0159edpov\u011Bd\u011Bt po\u0161kozen\u00ED koron\u00E1rn\u00EDch art\u00E9ri\u00ED pou\u017Eit\u00EDm neinvazivn\u00EDch parametr\u016F a bylo prok\u00E1z\u00E1no, \u017Ee hyperlipidemie a infarkt myokardu maj\u00ED nejvy\u0161\u0161\u00ED prediktivn\u00ED v\u00FDznam pro angio sk\u00F3re koron\u00E1rn\u00EDch tepen."@cs . "1"^^ . " virtual histology" . . " gene polymorphisms" . . " intravascular ultrasound" . "0"^^ . . "0"^^ . . . . . . . . . "Predikce rozsahu a slo\u017Een\u00ED aterosklerotick\u00FDch pl\u00E1t\u016F v koron\u00E1rn\u00EDch tepn\u00E1ch na z\u00E1klad\u011B ultrasonografick\u00E9ho vy\u0161et\u0159en\u00ED karotick\u00FDch tepen a polymorfizm\u016F vybran\u00FDch gen\u016F" . . " intima media thickness" . . "atherosclerosis" .