"The aim of the project is an evaluation of prognostic glycomarkers in head and neck squamous cell carcinomas. Immunohistochemistry, lectin histochemistry and reverse lectin histochemistry will be used methodically. Miscellaneous clinoco-pathological findings will be compared to the ascertained glycophenotype. The realtionship of the results of glycomic analysis to the survival parameters will be defined. The most beneficial glycobiologic prognostic factors will be determined. They will be finally included into the diagnostic-therapeutic schedule of head and neck cancer."@en . . " lectin" . . "2006-01-01+01:00"^^ . . . "http://www.isvav.cz/projectDetail.do?rowId=NR9049"^^ . . "Glycomic analysis of head and neck cancer - determination of prognostic relevance"@en . "head and neck cancer; prognostic factor; lectin; histochemistry; glycobiology"@en . . "2008-12-31+01:00"^^ . "Projekt si klade za c\u00EDl zhodnotit prognostick\u00FD v\u00FDznam glykobiologick\u00FDch marker\u016F u dla\u017Eicobun\u011B\u010Dn\u00FDch karcinom\u016F hlavy a krku. Metodicky bude zalo\u017Een na postupech imunohistochemick\u00FDch, na lektinov\u00E9 histochemii a reverzn\u00ED lektinov\u00E9 histochemii. R\u016Fzn\u00E9 klinickopatologick\u00E9 znaky budou srovn\u00E1v\u00E1ny se zji\u0161t\u011Bn\u00FDm glykofenotypem. D\u00E1le bude ur\u010Dov\u00E1n vztah v\u00FDsledk\u016F glykomov\u00E9 anal\u00FDzy k charakteristik\u00E1m p\u0159e\u017Eit\u00ED pacient\u016F. Po \u0159\u00E1dn\u00E9m statistik\u00E9m zhodnocen\u00ED z\u00EDskan\u00FDch v\u00FDsledk\u016F budou ur\u010Deny nejp\u0159\u00EDnosn\u011Bj\u0161\u00ED glykobiologick\u00E9 prognostick\u00E9 znaky a budou za\u0159azeny do diagnosticko-l\u00E9\u010Debn\u00E9ho schematu karcinom\u016F hlavy a krku." . . " histochemistry" . "2011-04-27+02:00"^^ . "2008-03-05+01:00"^^ . . " prognostic factor" . . . . "Galektin- 3 is important prognostic factor for time to progression and overal survival of patients with advanced head and neck cancer"@en . "0"^^ . . . . . . "Galektin - 3 je v\u00FDznamn\u00FD prognostick\u00FD faktor pro \u010Das do progrese a celkov\u00E9 p\u0159e\u017E\u00EDv\u00E1n\u00ED nemocn\u00FDch s pokro\u010Dil\u00FDmi n\u00E1dory hlavy a krku."@cs . "1"^^ . . "head and neck cancer" . "1"^^ . . "Glykomov\u00E1 anal\u00FDza karcinom\u016F hlavy a krku - stanoven\u00ED prognostick\u00E9ho v\u00FDznamu" . . "9"^^ . "NR9049" . "9"^^ . .