. "1"^^ . . "2008-09-16+02:00"^^ . "1"^^ . . . " Silness-L\u00F6e-index" . . . "0"^^ . . " periodontitis" . "Stav or\u00E1ln\u00EDho zdrav\u00ED u d\u011Bt\u00ED sledovan\u00FDch v programu ELSPAC Brno" . . . . "2007-03-02+01:00"^^ . . "2007-12-31+01:00"^^ . " DMFT-index" . "http://www.isvav.cz/projectDetail.do?rowId=NR8394"^^ . "Pr\u00E1ce studuje prevalenci zubn\u00EDho kazu, z\u00E1n\u011Btu d\u00E1sn\u00ED a parodontu u 800-1000 d\u011Bt\u00ED ve v\u011Bku 13-15 let za\u0159azen\u00FDch dp prograu ELSPAC s c\u00EDlem zjistit \u00FArove\u0148 or\u00E1ln\u00EDho zdrav\u00ED a stanovit strategii prevence t\u011Bchto multifaktori\u00E1ln\u00EDch chorob. V mikrobiologick\u00E9 \u010D\u00E1sti projektu bude u 150 d\u011Bt\u00ED s gingivitis a u 150 d\u011Bt\u00ED se zdravou d\u00E1sn\u00ED stanovena p\u0159\u00EDtomnost or\u00E1ln\u00EDch patogen\u016F, kter\u00E9 se mohou uplatnit v etiopatogenesi z\u00E1va\u017En\u00FDch syst\u00E9mov\u00FDch chorob. Budou vyu\u017Eity \u00FAdaje z ELSPAC datab\u00E1ze. C\u00EDlem projektu je zhodnotit mo\u017En\u00FD vliv polymorfism\u016F v genech ovliv\u0148uj\u00EDc\u00EDch z\u00E1n\u011Bt a tk\u00E1\u0148ovou remodelaci v etiopatogenezi gingivitis/parodontitis. Pou\u017Eit\u00E9 metody umo\u017En\u00ED posoudit i vztah genotypu k progresi choroby." . "V\u00FDsledky p\u0159in\u00E1\u0161ej\u00ED zcela nov\u00E9 poznatky t\u00FDkaj\u00EDc\u00ED se zejm\u00E9na diagnostick\u00FDch postup\u016F a \u00FAlohy genetiky v etiopatogenezi onemocn\u011Bn\u00ED parodontu."@cs . " genetics" . . "NR8394" . "Oral health state in children included in Brno ELSPAC study"@en . " gingivitis" . . "The results bring completely new knowledge related to especially diagnostic procedures and task of genetics in etiopatogenesis of paradont illness."@en . . . . "caries" . "2005-01-01+01:00"^^ . " microbiology" . "6"^^ . "6"^^ . . "caries; gingivitis; periodontitis; microbiology; genetics; DMFT-index; Silness-L\u00F6e-index; ELSPAC"@en . . "The project studies prevalence of the dental caries and gingivitis/periodontitis in 800-1000 children involed in ELSPAC study with the aim to find out the level of oral health and to determine strategy of prevention of these multifactorial diseses. Presence of oral pathogens, which can play a role in aethiology of severe systemic diseases, will be studied microbiologically in 150 children with healthy gingiva and in 150 children with gingivitis. The study will assess the contribution of polymorphism in genes which influence inflammation and tissue remodelling responses in aethiopathogenesis of chronic gingivitis/periodontitis. Relation of genotypes to disease progression will also be evaluated."@en . .