. " B-lymphocytes" . . "Bude analyzov\u00E1na exprese povrchov\u00FDch znak\u016F T- a B-lymfocyt\u016F, p\u0159edev\u0161\u00EDm t\u011Bch, kter\u00E9 jsou abnorm\u00E1ln\u00ED u nemocn\u00FDch s b\u011B\u017Enou variabiln\u00ED imunodeficienc\u00ED (CVID). Budou vy\u0161et\u0159eni zejm\u00E9na nemocn\u00ED se selektivn\u00EDm deficitem IgA, d\u00E1le deficitem IgM a CVID. V\u00FDsledky vy\u0161et\u0159en\u00ED subpopulac\u00ED T- a B- lymfocyt\u016F budou korelov\u00E1ny s dal\u0161\u00EDmi klinick\u00FDmi a laboratorn\u00EDmi \u00FAdaji ve snaze definovat podskupiny nemocn\u00FDch s deficitem IgA. Srovn\u00E1n\u00ED n\u00E1lez\u016F u pacient\u016F s CVID a selektivn\u00EDm deficitem IgA umo\u017En\u00ED hled\u00E1n\u00ED rozd\u00EDl\u016F vedouc\u00EDch k r\u016Fzn\u00E9mu fenotypick\u00E9mu vyj\u00E1d\u0159en\u00ED t\u011Bchto dvou chorob se stejn\u00FDm genetick\u00FDm z\u00E1kladem" . . . " T-lymphocytes" . "Abonormalities of T- and B-lymphocyte subpopulations in patients with CVID are partially age- and each-other related. Abnormalities in T- and B-lymphocyte charakterisic for CVID were only occasionally documented in patients with IgA or IgM deficiency."@en . "Abnormality T- a B lymfocyt\u00E1rn\u00EDch subpopulac\u00ED u neocn\u00FDch s CVID jsou \u010D\u00E1st. v\u011Bkov\u011B z\u00E1visl\u00E9 a \u010D\u00E1st. vz\u00E1jemn\u011B z\u00E1visl\u00E9. U nem. s deficitem IgA a IgM byly ptok\u00E1z\u00E1ny pouze ojed.abnormality T- a B- lymfocyt\u00E1rn\u00EDch subpopulac\u00ED typ. pro CVID."@cs . "NR7981" . "2007-08-08+02:00"^^ . . . "IgA deficiency; CVID; T-lymphocytes; B-lymphocytes; Differentiation antigens"@en . . "1"^^ . "1"^^ . "Lymfocyt\u00E1rn\u00ED subpopulace u pacient\u016F s humor\u00E1ln\u00EDmi imunodeficity" . "Lymphocyte subpopulatins in patients with humoral immunodeficiencies"@en . "0"^^ . "T- and- B- cell surface markers, namely those known to be abnormal in patients with common variable immunodeficiency (CVID), will be analysed in patients with selective IgA deficiency, selective IgM deficiency and CVID. The results of T- and B- cells subsets will be correlated with clinical and other laboratory data on order to determine subsets of IgAD patients. Comparison of the results obtained in patients with CVID and IgA deficiency will enable search for concords and differences in abnormalities leading to a different clinical manifestation of these diseases with the same genetic background."@en . . . . . . . . . . "5"^^ . . . "5"^^ . "IgA deficiency" . . . " CVID" . "http://www.isvav.cz/projectDetail.do?rowId=NR7981"^^ .