"2007-08-08+02:00"^^ . . . "Considering alternatives of the hilar structures protection prior to thermal impact of the probe during the Radiofrequency ablation of liver tumours."@en . "Study confirmed our hypothesis about protection of hilar structures by blood flow or by flow of cold saline. On the contrary clamping of portal vein increases effect and extent of RFA."@en . "Posouzen\u00ED mo\u017Enost\u00ED ochrany hilov\u00FDch struktur p\u0159ed tepeln\u00FDm p\u016Fsoben\u00EDm sondy p\u0159i radiofrekven\u010Dn\u00ED ablaci tumor\u016F jater." . . . . . . . "On the model of an animal, the application of the radio frequency ablation will be performed into the area of a liver parenchyma of a distance of approximately 1cm from the liver hilar. The animals, divided into the three groups, will undergo the RFA by a normal blood flowage in the portal vein (1). Further on using Pringle's maneuver (2) and by saline flowage, chilled on 10 degrees, in the portal vein (3). Then the USG Dopplerometery of the portal vein will be watched, specifically the the laboratory values ALP, GMT, ALT, AST and Bilirubin in the peripheral blood.After putting the models to death consecutively with a time interval, the histological examination will be carried out, focusing on the degree of damage to the venous wall and the gall duct wall."@en . "NR7909" . . "Potvrzen\u00ED hypot\u00E9zy, \u017Ee hilov\u00E9 struktury jsou chr\u00E1n\u011Bny proudem krve \u010Di chladn\u00E9ho fyziologick\u00E9ho roztoku. Naopak uzav\u0159en\u00EDm pr\u016Ftoku krve port\u00E1ln\u00ED \u017Eilou, zv\u00FD\u0161\u00EDme \u00FA\u010Dinnost RFA, ale riskujeme tromb\u00F3zu porty.Chladn\u00FD fyziologick\u00FD roztok sni\u017Euje celkov\u00E9 po\u0161kozen\u00ED"@cs . "Liver tumor" . . . . . " radiofrequency ablation" . "http://www.isvav.cz/projectDetail.do?rowId=NR7909"^^ . . "1"^^ . . . . " vein damage" . "Liver tumor; radiofrequency ablation; vein damage; bile duct damage"@en . "0"^^ . . "22"^^ . "0"^^ . "Na zv\u00ED\u0159ec\u00EDm modelu bude provedena aplikace radiofrekven\u010Dn\u00ED ablace do oblasti jatern\u00EDho parenchymu do vzd\u00E1lenosti cca 1cm od jatern\u00EDho hilu.Ve t\u0159ech skupin\u00E1ch budou zv\u00ED\u0159ata podrobena RFA p\u0159i norm\u00E1ln\u00EDm pr\u016Ftoku krve port\u00E1ln\u00ED \u017Eilou/1/. D\u00E1le p\u0159i Pringleho manevru /2/ a p\u0159i pr\u016Ftoku fyziologick\u00E9ho roztoku 10st. chladn\u00E9ho port\u00E1ln\u00ED \u017Eilou/3/.N\u00E1sledn\u011B bude sledov\u00E1no USG Dopplerometrie port\u00E1ln\u00ED \u017E\u00EDly,laboratorn\u00ED hodnoty ALP,GMT,ALT,AST a bilirubinu v perifern\u00ED krvi. N\u00E1sledn\u011B s \u010Dasov\u00FDm odstupem bude po usmrcen\u00ED modelu provedeno histologick\u00E9 vy\u0161et\u0159en\u00ED zam\u011B\u0159en\u00E9 na stupe\u0148 po\u0161kozen\u00ED \u017E\u00EDln\u00ED st\u011Bny a st\u011Bny \u017Elu\u010Dovodu." . "22"^^ . .