" mtDNA" . . " energy conversion" . . . " mitochondria" . "http://www.isvav.cz/projectDetail.do?rowId=NR7790"^^ . "Charakterizace molekul\u00E1rn\u011B etioatogenn\u00EDch mechanizm\u016F vzniku mitochondri\u00E1ln\u00EDch chorob na podklad\u011B specifick\u00FDch defekt\u016F mitochondri\u00E1ln\u00ED ATP synt\u00E1zy vyvolan\u00FDch r\u016Fzn\u00FDmi mutacemi v mtDNA ATP6 genu nebo defekty biosynt\u00E9zy enzymu jadern\u00E9ho p\u016Fvodu." . "ATPase" . . . " inherited diseases" . . . "Mitochondrial diseases caused by inherited disorders of ATP synthase"@en . "14"^^ . "14"^^ . . " oxidative phosphorylation" . . . " mutation" . . "ATPase; mitochondria; mtDNA; mutation; oxidative phosphorylation; inherited diseases; energy conversion; biogenesis"@en . "Studium poruch ATP synt\u00E1zy objasnilo p\u016Fsoben\u00ED 2bp-delece ATP6 genu, charakterizovalo fenotyp defekt\u016F jadern\u00E9ho p\u016Fvodu a uk\u00E1zalo, \u017Ee defekty enzymu vedou k energetick\u00E9 deprivaci a zv\u00FD\u0161en\u00E9 tvorb\u011B ROS."@cs . "Studies of ATP synthase disorders charasterized 2-bp deletion in ATP6 gene, phenotype of enzyme defects of nuclear origin and showed that these defects cause energy deprivation and enhanced ROS production."@en . "1"^^ . . "Characterization of molecular etiopathogenic mechanisms of mitochondrial diseases that are caused by specific defects of mitochondrial ATP synthase due to different mutations in mtDNA ATP6 gene, or by nuclear defects affecting biosynthesis of the enzyme."@en . . "0"^^ . . . . . "NR7790" . "0"^^ . . . "Mitochondri\u00E1ln\u00ED choroby na podklad\u011B d\u011Bdi\u010Dn\u00FDch poruch ATP synt\u00E1zy" . . . "2007-08-08+02:00"^^ .