"Goal of the project is to clarify relationships of the markers of inflammation and thrombosis with adipose tissue distribution after the short term in-patient weight reducing regimen and after a long-term weight loss. Next goal is to identify the effect of body composition and markers of inflammation on the composition of fatty acids in serum and adipose tissue after the short term in-patient weight reducing regimen and after a long-term weight loss. The last goal is to identify the cases of single gene mutations as etiology of severe obesity in the Czech Republic."@en . "Body fat distribution in obese subjects and metabolic syndrome, pathogenesis, possibilities of change by obesity treatment. Single gene mutation assessment in grossly obese patients."@en . . "2004-01-01+01:00"^^ . . "V\u00FDsledek s mo\u017En\u00FDm praktick\u00FDm dopadem. Prok\u00E1zan\u00FD vztah mezi slo\u017Een\u00EDm mastn\u00FDch kyselin krevn\u00EDch lipid\u016F a suplementac\u00ED omega 3 mastn\u00FDmi kyselinami p\u0159i reduk\u010Dn\u00ED diet\u011B."@cs . "http://www.isvav.cz/projectDetail.do?rowId=NR7782"^^ . "2007-12-31+01:00"^^ . . "7"^^ . "7"^^ . " genetics" . "2007-03-01+01:00"^^ . "NR7782" . . " fat distribution" . . . "P\u0159edm\u011Btem projektu je stanoven\u00ED vztahu marker\u016F z\u00E1n\u011Btu (TNF-alfa, IL-6, protein\u016F akutn\u00ED f\u00E1ze) a tromb\u00F3zy (cytoadhezivn\u00ED molekuly) k distribuci tukov\u00E9 tk\u00E1n\u011B po kr\u00E1tkodob\u00E9m reduk\u010Dn\u00EDm re\u017Eimu za hospitalizace a po dlouhodob\u00E9m \u00FAbytku hmotnosti. Dal\u0161\u00EDm c\u00EDlem je stanovit vliv distribuce tukov\u00E9 tk\u00E1n\u011B a slo\u017Een\u00ED t\u011Bla na slo\u017Een\u00ED mastn\u00FDch kyselin lipid\u016F v s\u00E9ru a tukov\u00E9 tk\u00E1ni ve vztahu k ukazatel\u016Fm z\u00E1n\u011Btu po kr\u00E1tkodob\u00E9 a po dlouhodob\u00E9 redukci hmotnosti. C\u00EDlem je rovn\u011B\u017E zji\u0161t\u011Bn\u00ED v\u00FDskytu monogenn\u00EDch mutac\u00ED jako p\u0159\u00ED\u010Diny t\u011B\u017Ek\u00E9 obezity v \u010CR." . . . . " monogenic mutations" . . . . . . "The result with a possible practical effect. Proved relationship between the composition of fats of blood lipides and supplement of omega 3 fats during the lowering diet."@en . "2008-09-16+02:00"^^ . . "1"^^ . " inflammation" . . "1"^^ . . "obesity; fat distribution; fatty acids; inflammation; monogenic mutations; genetics; obesity treatment"@en . "obesity" . . "Distribuce tuku u ob\u00E9zn\u00EDch osob a metabolick\u00FD syndrom, etiopatogeneze, mo\u017Enosti ovlivn\u011Bn\u00ED l\u00E9\u010Dbou obezity. Monogenn\u00ED mutace jako p\u0159\u00ED\u010Dina t\u011B\u017Ek\u00E9 obezity." . " fatty acids" . "0"^^ .