"http://www.isvav.cz/projectDetail.do?rowId=NM7719"^^ . "vWF-depolymeraze" . "Thrombotic thrombocytopenic purpura: molecular-biological diagnosis"@en . "multimers vWF" . . "0"^^ . . . . "Byla zavedena molekul\u00E1rn\u011B-genet.diagnostika TTP.Byla provedena diferenci\u00E1ln\u00ED diagn.pacient\u016F s vrozenou a z\u00EDskanou formou TTP a trombo-mikroangiopati\u00ED (HUS).Byly nalezeny kauz\u00E1ln\u00ED mutace vrozen\u00E9 TTP a zhodnoceny ukazatele pr\u016Fb\u011Bhu onemocn\u011Bn\u00ED."@cs . . "TF-bearing microparticles" . . . . . . . "2006-06-23+02:00"^^ . "In our molecular-biological study of diagnosis of TTP we will focus on establisment of assays which determine activity of the vWF cleavage protease and its auto antibody. We shall establish methods for searching of mutation in gene for vWF protease. (ADAMST13) and we will folow up markers of hypercoagulation during a various states of disease."@en . "V r\u00E1mci molekul\u00E1rn\u011B-genetick\u00E9 diagnostiky TTP budeme zav\u00E1d\u011Bt metodiky na stanoven\u00ED aktivity depolymer\u00E1zy VWF a jej\u00EDho inhibitoru, metodiky na DNA anal\u00FDzu genu pro depolymer\u00E1zu (ADAMST13) a hyperkoagula\u010Dn\u00ED ukazatele v pr\u016Fb\u011Bhu remise i onemocn\u011Bn\u00ED." . . "Molecular-biolog.methods were established for diagnosis of TTP.They were used to distinguish an inherited,acquired TTP and other thrombo-micorangiopat.(HUS).We determined causal mutations of familial TTP and evaluated markers of disease process."@en . "Molekul\u00E1rn\u011B-biologick\u00E1 diagnostika trombotick\u00E9 trombocytopenick\u00E9 purpury." . "von Willebrand Factor" . . . "TTP" . "NM7719" . . . "activation of coagulation" . . . "ADAMST13" . "5"^^ . "5"^^ . . "0"^^ . "TTP;vWF-depolymeraze;ADAMST13;von Willebrand Factor;multimers vWF;TF-bearing microparticles;activation of coagulation;microtrombi"@en . . "1"^^ .