"Komplexn\u00ED sekven\u010Dn\u00ED anal\u00FDza cDNA pro lidsk\u00FD ameloblastin a odvozen\u00ED \u00FApln\u00E9 struktury proteinu a v\u0161ech jeho vatiant. Konstrukce expresn\u00EDho vektoru a exprese lidsk\u00E9ho ameloblastinu,jeho purifikace,p\u0159\u00EDprava protil\u00E1tek a identifikace proteinu v tk\u00E1ni. Hled\u00E1n\u00ED dal\u0161\u00EDch dosud nezn\u00E1m\u00FDch protein\u016F,kter\u00E9 ovliv\u0148uj\u00ED proces formov\u00E1n\u00ED mineralizovan\u00FDch tk\u00E1n\u00ED a mohou vykazovat interakci s ameloblastinem a modifikovat jeho funkci. Prov\u011B\u0159en\u00ED v\u00FDskytu a funkce ameloblastinu m\u00EDsto matrix zubn\u00ED skloviny,jmenovit\u011B v oblasti zubn\u00EDho cementu a Hertwigov\u00FDch epitheli\u00E1ln\u00EDch pochev." . "http://www.isvav.cz/projectDetail.do?rowId=NM6093"^^ . "Lidsk\u00FD ameloblastin" . . . "Ameloblasta" . "Human ameloblastin"@en . "NM6093" . "Molekul\u00E1rn\u011B genetick\u00E1 studie lidsk\u00E9ho ameloblastinu, d\u00E1le pak imunodetekci proteinu in situ. Publikace: Bratislava Medical Journal"@cs . . . . "mRNA" . . . . "Protein sequence" . . . . . . "2003-07-31+02:00"^^ . . "Matrix" . "Enamel" . "Ameloblastin" . "0"^^ . . . "1"^^ . "0"^^ . "1"^^ . "cDNA sequence" . . "1"^^ . . "Ameloblastin;Matrix;Ameloblasta;Enamel;mRNA;cDNA sequence;Protein sequence;Expression"@en . "Complete sequence analysis of the cDNA for the human ameloblastin,protein sequence estimation with all ist variants. Conctruction of the expression vector and expression of human ameloblastin,ist purification,antibody preparation and identification of ameloblastin in tissue. Search for unknown proteins that may have influence on mineralized tissue formation and may interact with ameloblastin and modify its function. Verification of the occurance and function of ameloblastin in tissue different from the enamel matrix,mamely in the cementum and in the epithelial root sheaths."@en .