"1"^^ . "Byl vypracov\u00E1n postup jak bezpe\u010Dn\u011B posoudit p\u0159\u00EDtomnost metabolit\u016F opioid\u016F v mo\u010Di delikvent\u016F. Publikace : tuzemsk\u00E9"@cs . . . "NL4730" . . "9"^^ . . "9"^^ . "Biotransformace a dispozice dihydrokodeinu a dal\u0161\u00EDch opi\u00E1t\u016F u \u010Dlov\u011Bka. Interpretace analytick\u00FDch n\u00E1lez\u016F ve forenzn\u00ED toxikologii" . "The biotransformation of dihydrocodeine in man after oral therapeutic dose will be studied,the new metabolites will be searched and their elimination in urine in the time course evaluated. The effects of codeine or hydrocodome,applied concomitantly to dihydrocodeine,will be studied too. The toxicological methods available will be modified and optimizeh for quantitativw evaluation of presence of individual metabolites. The results of experimental studies of elimination will be compared to findings of case reports concerning the application of illegal mixture %22Brown%22."@en . . . . . . "Bude up\u0159esn\u011Bna biotransformace dihydrokodeinu u \u010Dlov\u011Bka po terapeutick\u00E9 d\u00E1vce, hled\u00E1ny nov\u00E9 metabolity,hodnoceno zastoupen\u00ED metabolit\u016F v mo\u010Di v pr\u016Fb\u011Bhu \u010Dasu,sledov\u00E1no ovlivn\u011Bn\u00ED zastoupen\u00ED metabolit\u016F po pod\u00E1n\u00ED kodeinu nebo hydrokodonu vedle dihydrokodeinuToxikologick\u00E9 metody budou modifikov\u00E1ny a optimalizov\u00E1ny pro kvantitativn\u00ED hodnocen\u00ED zastoupen\u00ED jednotliv\u00FDch metabolit\u016F. V\u00FDsledky experiment\u00E1ln\u00EDch vylu\u010Dovac\u00EDch studi\u00ED budou porovn\u00E1ny s n\u00E1lezy po aplikac\u00EDch ileg\u00E1ln\u00ED sm\u011Bsi%22Brown%22 v konkr\u00E9tn\u00EDch kazuistik\u00E1ch" . . . . "http://www.isvav.cz/projectDetail.do?rowId=NL4730"^^ . . "Biotransformation and disposition of dihydrocodeine and other opiates in man.Interpretation of analytical findings inforensic toxicology"@en . "0"^^ . "0"^^ . .