"Analysis and evaluation of the novel biochemical parametres for determination of hepatocytes metabolic function in transplant patients (lidocaine test, IGFBP-3, aminoacids). Analysis and evaluation of the novel biochemical parametres for determination kidney function in transplant patients (cystatin C, aminoacids). Evaluating of immunosuppresive drugs (mycophenolate mofetil). Analysis and evaluation of the tests available for monitoring nefrotoxicity and hepatotoxicity of these drugs. Evaluating of determination of the novel biochemical parametres for determination acute rejection after organ transplantation (neopterin, plasma DNA)."@en . "5"^^ . "Sledov\u00E1n\u00ED s\u00E9rov\u00FDch hladin cystatinu C, IGFBP-3 a plasmatick\u00E9 DNA jako ukazatel\u016F org\u00E1nov\u00E9ho posti\u017Een\u00ED" . "5"^^ . . . . "Monitoring of serum cystatin C, IGFBP-3 and plasma DNA as a marker of organ impairment"@en . . . "metabolic" . . "immunosupressive" . . . . . "cystatin C;IGFBP-3;liver;kidney;metabolic;lidocain;immunosupressive;plasma DNA"@en . "Anal\u00FDzy a evaluace nov\u00FDch biochemick\u00FDch test\u016F k posouzen\u00ED metabolick\u00FDch funkc\u00ED hepatocyt\u016F u pacient\u016F v transplanta\u010Dn\u00EDm programu (nap\u0159. lidocainov\u00FD test, IGFBP-3, aminokyseliny). Anal\u00FDza a evaluace nov\u00FDch biochemick\u00FDch test\u016F k posouzen\u00ED ren\u00E1ln\u00EDch funkc\u00ED u pacient\u016F v transplanta\u010Dn\u00EDm programu (nap\u0159. cystatin C, aminokyseliny). Anal\u00FDzy a evaluace stanoven\u00ED imunosupresiv (nap\u0159. mykofenol\u00E1t Mofetil), anal\u00FDza a evaluace test\u016F vhodn\u00FDch k monitorov\u00E1n\u00ED jejich nefrotoxicity a hepatotoxicity. Anal\u00FDzy a evaluace nov\u00FDch biochemick\u00FDch test\u016F k posouzen\u00ED akutn\u00ED rejekce po transplantaci org\u00E1n\u016F (nap\u0159. neopterin, plazmatick\u00E1 DNA)." . . "liver" . "0"^^ . . "cystatin C" . . "IGFBP-3" . "Zaveden\u00ED laboratorn\u00EDch metod do klinick\u00E9 praxe."@cs . "0"^^ . "lidocain" . "NK6447" . . . "1"^^ . "kidney" . . "http://www.isvav.cz/projectDetail.do?rowId=NK6447"^^ . "2004-07-12+02:00"^^ .