. . . "Patogenn\u00ED kmeny kvasinek rodu Candida: typizace a charakterizace sekretovan\u00FDch proteas" . . "NI6485" . . "Candida isolates from routine clinical screening will be identified, typed by RAPD and screened for secreted proteinase production. Odds method will be modified for rapid monitoring of proteinase secretion by Candida cultures. Inhibitors of Candida secreted proteinases will be designed and tested in vitro with purified enzymes using spectrophotometric assay. Effect of these inhibitors on growing Candida cultures will be examined using modified Odds method."@en . . "0"^^ . "Pathogenic Candida strains: typing and characterization of secreted proteinases"@en . . . . "3"^^ . "Isol\u00E1ty kvasinek rodu Candida z klinick\u00E9ho materi\u00E1li budou identifikov\u00E1ny typizov\u00E1ny a testov\u00E1ny na produkci sekretovan\u00FDch proteas. Oddsova metoda bude modifikov\u00E1na pro \u00FA\u010Dely rychl\u00E9ho monitoringu sekrece proteas kandidami. Budou navr\u017Eeny, syntetizov\u00E1ny a testov\u00E1ny inhibitory proteas sekretovan\u00FDch kandidami. Bude testov\u00E1n vliv inhibitor\u016F na purifikovan\u00E9 proteasy i na rostouc\u00ED kulturu kandid." . "secreted proteinase" . "3"^^ . . . "1"^^ . . "1"^^ . "2004-07-12+02:00"^^ . "proteinase inhibitors design" . "RAPD" . . . . "candida;proteinase inhibitors design;RAPD;secreted proteinase;biotyping methods"@en . "candida" . "http://www.isvav.cz/projectDetail.do?rowId=NI6485"^^ . "Zaveden\u00ED pevn\u00E9 agarov\u00E9 p\u016Fdy , p\u0159\u00EDsp\u011Bvek k epidemiologii kvasinek."@cs . .