"Imunn\u00ED heparinem indukovan\u00E1 trombocytopenie (HIT-II) - ov\u011B\u0159en\u00ED mo\u017En\u00E9 vazby specifick\u00E9 protil\u00E1tky i na jin\u00E9 minoritn\u00ED antigeny: interleukin 8 (IL-8(, neutrofily aktivuj\u00EDc\u00ED peptid 2 (NAP - 2) a jejich komplexy s jednotliv\u00FDmi druhy heparin\u016F. Imunn\u00ED heparinem indukovan\u00E1 trombocytopenie (HIT-II) - ov\u011B\u0159en\u00ED dostate\u010Dn\u00E9 specifity a sensitivity stanoven\u00ED uvoln\u011Bn\u00E9ho serotoninu z aktivovan\u00FDch desti\u010Dek chromatografickou metodou u pacient\u016F s HIT-II. Imunn\u00ED heparinem indukovan\u00E1 trombocytopenie (HIT-II) - zaveden\u00ED citliv\u00FDch diagnostick\u00FDch laboratorn\u00EDch test\u016F v \u010CR, vypracov\u00E1n\u00ED metodiky k laboratorn\u00EDmu potvrzen\u00ED syndromu." . "platelet factor 4" . "3"^^ . . . "0"^^ . "Interleukin -8" . "NI6063" . "3"^^ . "Heparin;thrombocytopenia;thrombosis;antibodies;platelet factor 4;Interleukin -8;Neutrophill acivating peptide"@en . . "2003-07-31+02:00"^^ . . "0"^^ . . "thrombocytopenia" . . "\u00DAloha interleukinu-8 a dal\u0161\u00EDch cytokin\u016F v patogenezi heparinem indukovan\u00E9 trombocytopenie" . "thrombosis" . . . . "Heparin-induced immune-mediated thrombocytopenia (HIT-II) - possible reactivity of the specific antibody against other minor antigens, such as interleukin -8, neutrophill-activating peptide -2 and their complexes with different types of heparin. Heparin - induced immune-mediated thrombocytopenia (HIT- II) - verification of the possibility to measure serotonin release in patients with HIT- II by high performance liquid chromatography (HPLC) - fluorimetric detection. Heparin-induced immune-mediated thrombocytopenia (HIT-II) - introduction of reliable, sensitive and highly specific diagnostic assays for laboratory confirmation of HIT-II in Czech republic."@en . "A Role of Interleukin 8 and other cytokines in the Pathogenesis of the Heparin- induced Thrombocytopenia"@en . "antibodies" . "Heparin" . . . . "http://www.isvav.cz/projectDetail.do?rowId=NI6063"^^ . . "1"^^ . "Bylo prok\u00E1z\u00E1no,\u017Ee komplexy IL-8 a NAP-2 s heparinem se mohou d\u00EDky struktur\u00E1ln\u00ED podobnosti s PF4 tak\u00E9 uplatn\u0148ovat tak\u00E9 v patofyziologii HIT,ale pouze okrajov\u011B. Zaveden\u00EDm citliv\u00FDch serologick\u00FDch a funk\u010Dn\u00EDch test\u016F je mo\u017En\u00E9 zlep\u0161it mo\u017Enostlaboratorn\u00ED"@cs . . . .